Connect with us


Can drugs suppress suicidal ideation in children with ADHD?


A longitudinal cohort study found that drugs used to treat attention deficit / hyperactivity disorder (ADHD) were associated with a reduced suicide rate in children who externalized the symptoms of the condition. ..

ADHD drug use was associated with reduced suicide behavior in children aged 9 to 11 years with more severe externalized symptoms such as hyperactivity, oppositional defiantness, and other symptoms of conduct disorder (significant). Symptomatology and drug interaction B = -0.250, SE = 0.086 P = 0.004), reported by Ran Barzilay, MD, PhD, and colleagues at the Philadelphia Children’s Hospital.

Not only that, there was a significant association between symptom externalization and suicide rate in children not treated for ADHD (symptom 1 SD change, OR 1.42, 95% CI 1.33-1.52). , P <0.001), the author JAMA network open..

However, for children taking this drug for symptoms, there was no significant association between symptoms and suicide rate (OR 1.15, 95% CI 0.97-1.35, P = 0.10), they added.

In the analysis of Adolescent Brain Cognitive Development (ABCD) Studies Based on the data, researchers conducted a one-year follow-up analysis to determine how ADHD treatment affected the association between baseline externalization of children and reporting of suicidal tendencies.

The average age of participants was about 10 years, with 52.2% being boys. About three-quarters of children were white. Drugs for ADHD included methylphenidate (Ritalin) and amphetamine derivatives, an α-2 agonist, and atomoxetine (Stratera).

At baseline, it contained 11,878 children. Of these, 1,060 were treated for ADHD and 1,040 reported past or present suicidal ideation or emotions. More boys reported suicidal behavior than girls (58.0% and 42.0%, respectively), but there was no difference in suicidal reports among children of different race / ethnic backgrounds.

Adjusted analysis found both ADHD treatments (OR 1.32, 95% CI 1.06-1.64, P= 0.01) and externalization of symptoms (OR 1.34, 95% CI 1.26-1.42, P<0.001) was associated with suicidal tendencies.

In line with previous trends, the study found that at 1 year of age, children with strong extrinsic symptoms who were on ADHD at baseline were less likely to report suicidal behavior ( Significant symptomatology-drug interaction B = -0.34, SE = 0.18, one-sided test P = 0.03).

And for children who did not take medication at baseline, the authors found an association between higher externalized symptoms and a higher probability of reporting suicidal feelings (OR 1.33, 95% CI 1.14-1.55). , P <0.001). Investigators say these links were observed in both boys and girls alike.

“Our findings address a significant childhood suicide knowledge gap,” wrote Bargeley and colleagues, who have seen a rapid increase in childhood suicide cases over the last decade. “The results provide simple and viable goals for optimizing prevention plans and intervention strategies for elementary school children with externalization problems.”

According to them, the significant limitations of this study cannot explain the number of high-risk children who may have received other forms of mental health treatment or intervention that may have influenced the outcome. That’s what it means.

Researchers suggest that future analysis of ABCD study data should be conducted to better understand adolescent suicidal ideation rates, which increase the rate of suicidal ideation.

  • Author['full_name']

    Kara Grant In February 2021, he joined MedPage Today’s Enterprise & Investigative Reporting team. She is in charge of psychiatry, mental health and medical education. follow us


The study was supported by grants from the National Institute of Mental Health, the Philadelphia Children’s Hospital Lifelong Brain Institute, and the University of Pennsylvania Pennsylvania Institute.

Barzilay has revealed a financial relationship with Taliaz Health, the mental health platform for artificial intelligence.

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos

Pictures Credit


to request, modification Contact us at Here or [email protected]