Connect with us

Health

A new way to understand the complex rhythms of the brain

Published

on


Currently as a researcher For long, tricky experiments in the lab, you can spend the day listening to music and podcasts. But in the early days of neuroscience, hearing was an important part of this process. To understand what a neuron is interested in, researchers convert the near-instantaneous signal (called a “spike”) that a neuron sends into sound. The louder the sound, the more frequent the neuron’s signal and the higher the firing rate.

“You can hear how big the speaker is, whether it’s really big or really quiet,” said Joshua Jacobs, an associate professor of biomedical engineering at Columbia University. “This is a very intuitive way to see how active a cell is. The way.”

Neuroscientists no longer rely on sound. Embedded electrodes and computer software can be used to accurately record spikes. To explain the firing rate of neurons, neuroscientists choose a time frame (for example, 100 milliseconds) and look at the number of firings. Scientists have discovered most of our understanding of how the brain works through firing rates. For example, a deep examination of the brain called the hippocampus revealed place cells. These cells become active when the animal is in a specific position. This discovery in 1971 won the 2014 Nobel Prize for neuroscientist John O’Keefe.

Emissivity is a convenient simplification. It shows the overall activity level of the cell, at the expense of accurate information about peak hours. However, the individual spike sequences are so complex and diverse that it is difficult to understand what they mean. Therefore, Peter Latham, a professor of computational neuroscience at the University College London, said that the focus on emissivity usually results in practical ones. “There is not enough data. We did, “says Latham. “Every attempt is completely different.”

But that doesn’t mean it doesn’t make sense to study peak hours. Neuronal spikes are difficult to interpret, but once you know what you’re looking for, you can find meaning in these patterns.

This was the creation of O’Keefe in 1993, more than 20 years after the place cells were discovered.By comparing the time of excitement of these cells with local vibrations (overall wave-like activity patterns in the brain region), he found a species. “Phase pre-session”. When the mouse is in a particular location, the neurons fire at the same time when other nearby neurons become most active. However, as the mouse continues to move, the neurons gradually activate before and after the peak activity of their neighbors. Over time, as neurons become more and more out of sync with their neighbors, phase shifts occur. Ultimately, background brain activity follows a repetitive up-and-down pattern that regains synchronization before resuming the cycle.

Since the discovery of O’Keefe, people have conducted extensive research on phase aging in rats. But until Jacobs’ team published an article in the journal in May, no one was confident that it would happen to humans. cell this First evidence in the human hippocampus“This is good news because the situation is changing under different species and different conditions,” said Mayank Mehta, a well-known phase aging researcher at the University of California, Los Angeles, who was not involved in the study. Said.

A team at Columbia University discovered a finding in a 10-year-old epilepsy patient’s brain record that tracked the patient’s neural activity navigating a virtual environment on a computer. Epilepsy patients are often employed in neuroscience research because treatment of epilepsy patients may include surgical implantation of deep brain electrodes.

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos



Pictures Credit

ExBUlletin

to request, modification Contact us at Here or collaboratio[email protected]