The situation with COVID-19 in Brazil has opened the door to the emergence and epidemic of relatively new fungi that are rapidly showing signs of becoming drug-resistant “superfungi.” Fungal journal..
Researchers have detected since December 2020 Candida auris Nine patients at a hospital in Salvador, northeastern Brazil.
Usually a genus fungus Candida It is relatively harmless and most often causes treatable vaginal yeast infections and oral candidiasis. However, the mortality rate is close to 60%, Candida auris Patients with SARS-CoV-2 have different symptoms and are ideal targets.
Candida auris It can enter the bloodstream and cause a systemic infection known as candidaemia, which resembles bacterial sepsis. Invasion of the bloodstream and poor response of the immune system to pathogens can damage several organs and eventually lead to death.
“This species is not very sensitive to disinfectants used in hospitals and clinics,” said Arnaldo Colombo, lead author of the new study and director of the Institute of Special Mycology at the Federal University of São Paulo (UNIFESP). explained. , It can survive in hospitals, where it colonizes healthcare professionals and eventually infects patients with severe COVID-19 and other important patients with long-term stays. “
Of the nine patients in the hospital, Colombo said some had shown colonization of the fungus and others were infected and symptomatic.
“We are monitoring the evolutionary characteristics of Candida auris Samples that have been isolated from patients in Salvador hospitals and have reduced susceptibility to fluconazole and echinocandin have already been found. The latter belongs to a major class of drugs used to treat invasive candidiasis, “says Colombo.
In fact, Colombo and his team have been testing hospital samples of antifungal susceptibility every month since December 2020. In a recent sample, researchers were able to inactivate the culture last year, and even earlier this year.
“Like many antibiotic-resistant bacteria, the mechanism by which a species develops drug resistance is not enzymatic degradation. Fungi develop structural changes in the proteins to which the drug binds and block the cell wall. The key synthesis of survival. “
UNIFESP’s Colombo group is now working with a Dutch colleague to sequence the fungus and confer drug resistance on the gene. Candida auris It has been mutated from December 2020 to the present.
Candida auris It was first separated in Japan in 2009, in Asia and Europe in 2011, in the Americas, Colombia, Panama, Chile in 2016, and in Brazil in 2020. So far, five clades or strains of fungi have been described.
According to Colombo, the salvador-isolated clades are more similar to the original Asian clades than the variants found in Venezuela and other South American countries, suggesting the second independent arrival of superfungi on the continent. I am.
“Or, there may be local sources of the environment, as none of the Brazilian patients infected with the fungus have traveled abroad or been infected with relatives,” Colombo said.
Due to the second wave of COVID-19 infection in Brazil, the research team is particularly concerned about hyperfungi, regardless of origin.
“In the near future, over-occupancy and limited resources for infection control practices, such as long-term use of personnel protection due to shortages, Candida auris To spread invasive devices, form colonies, and explode medical-related infections, “the team concludes.
Photo: Fluorescence microscope image showing morphology Candida auris.. credit: João Nóbrega Almeida Júnior / UNIFESP
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
to request, modification Contact us at Here or [email protected]
- Ukraine frontline: Soldiers dig trenches under fear of Russian snipers | BBC Newsnight
- Moment fire rips through Iraqi wedding
- ARPA-H Fast Tracks Development of New Cancer Implant Tech – News
- Benjamin Netanyahu: Israel judges review law which could oust PM – BBC News
- 90,000 residents flee Nagorno-Karabakh amidst uncertain future
- What Employers Should Know About Workers Who Have Long COVID-19
- M53 crash: Teen girl and driver killed after school bus overturns in UK – BBC News
- When’s the Best Time to Get the Updated COVID Shot?
- Teenage girl killed in Croydon named
- Moment fast food worker draws gun on customer over ‘missing fries’ – BBC News
- Prostate cancer trial: Radiotherapy doses can be cut safely
- 20mph zones could be curbed by Rishi Sunak