Tens of thousands of people may need kidney dialysis or transplants due to the coronavirus, according to experts warning that Covid’s long-term effects are causing an epidemic in primary care.
Up to 90% of coronavirus patients admitted to the hospital may still experience symptoms after two to three months, ranging from shortness of breath to joint pain, fatigue and chest pain, scientists told the Lords Science and Technology Committee on Tuesday.
Donal ODonoghue, a consultant kidney doctor at Salford Royal NHS Trust, said kidney damage is a major concern. He believes the virus can directly attack organs, he said, and that the kidneys could also be damaged by systemic inflammation caused by the virus.
In general, about 20% of people who go to intensive care units need to undergo dialysis. It was up to 40% during Covid and 85% of people had some degree of kidney damage. This is probably happening in the community as well.
ODonoghue said it is not known how many of these patients will develop more severe kidney disease, but the numbers could be high. There may be tens of thousands or more people who need dialysis. [or] He added that about 6,500 people were accepted into dialysis and transplant programs in a normal year.
Tom Solomon, professor of neurology at the University of Liverpool, told the committee more work is needed to support Covid survivors. [GPs] He added that he sees a lot of patients left with problems due to Covid, and should be able to recommend them so they can help them understand what’s going on. This is actually the current trend in primary care.
Chris Brightling, professor of respiratory medicine at the University of Leicester, who leads the Phosp-Covid study of the long-term effects of the disease, said the study in Italy provided additional clues about the magnitude of the viral persistence effect.
This, he said, suggests that only about 10 to 15 percent have no persistent symptoms, even when looking at people hospitalized two to three months after discharge.
Brightling said pilot data from full-body scans of 50 patients in the Phos-Covid and C-MORE studies showed a broader physiological impact of Covid-19.
[These] The kidneys, liver, lungs, and heart show terminal organ damage, and less damage in the brain. This is affecting more than a third of individuals at the time of two months, he said. We’re getting a lot of clues that there are things happening in many organs with diseases that initially start with respiratory infections.
While much of the current study is based on people hospitalized with Covid-19, Brightling warns that long-term effects, especially problems such as fatigue and chronic pain, are likely to be present in people with mild forms of the disease.
Some of them may have pneumonia and have not been hospitalized, he said, but many may have a wider range of inflammatory effects that can affect many many organs in the body.
Brightling said the important question was whether some conditions could get worse over time, such as early kidney damage or a new onset of diabetes. It will certainly be of interest to people in the community, he said.
Experts who provide evidence to the committee also stressed that Covid’s effects on the body could lead to neurological problems, including stroke and brain inflammation. This disease has also been linked to mental health problems in both people with and without the disease.
Sebastian Brandner, professor of neuropathology at University College London, says more autopsies are needed to understand how the disease affects the central nervous system.
If a patient is known to have died from Covid, a coroner autopsy is usually not required. However, with the consent of the deceased family, an autopsy can be performed for medical research.
During this entire Covid-19 outbreak, Brandner said there were just over 12 or 20 post-mortem analyzes with brains available for analysis. Of the patient.
With resources realigned and morgues not overwhelmed, Brandner said it was important to conduct such research.
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