Health
What you need to know about boosters when you get the Johnson & Johnson vaccine
Without solid data on the long-term efficacy of the Johnson & Johnson vaccine, it would be difficult for health officials to recommend boosters, said John Moore, a virologist at Weil Cornell Medicine. “What can you do if you’re making data-driven decisions and you don’t have the data?” He said. “This is a kind of dilemma. Public confidence in vaccines generally depends on looking at how sausages are made and ensuring that they are a data-driven, transparent process. I am. “
How effective is the Johnson & Johnson vaccine?
In clinical trials conducted before the spread of the delta variant, the Johnson & Johnson vaccine Was 72% effective In the United States as a whole About 95% effectiveness Of Pfizer and Moderna vaccines. However, it is difficult to make a direct comparison of vaccines tested at different locations and at different times.
All available vaccines appear to lose some effectiveness against deltas, which may be able to dodge some of the antibodies in the immune system. The Johnson & Johnson vaccine is no exception. “Because it’s always there, you’d expect some resistance to Delta,” said Dr. Moore.
Small laboratory studies have shown contradictory results on how well the Johnson & Johnson vaccine protects against Delta. last month, Johnson & Johnson said A single dose of the vaccine stimulated a strong immune response to Delta, which lasted at least 8 months.
But the data from Another recent laboratory study A single dose of the vaccine elicited a relatively weak antibody response to Delta, suggesting that it may make boosters more essential.
The first real-world data on the effectiveness of the vaccine against mutants was released this month.Preliminary results from clinical trials of approximately 500,000 healthcare workers in South Africa show that a single dose of the vaccine Up to 96 percent effectiveness 71 percent for deaths and hospitalizations from infectious diseases caused by Delta.
“It was a very large analysis and very clear results, and the single-shot J. & J. Vaccine provided substantial protection against delta mutants,” said Johnson & Johnson’s study. Dr. Danbaroch, a virologist at the Beth Israeli Cones Medical Center in Boston, who was not involved in the South African trial, said.
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