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Coronavirus: COVID-19 vaccine can boost immunity in former SARS patients, studies find

Coronavirus: COVID-19 vaccine can boost immunity in former SARS patients, studies find

 


Researchers in Toronto-Singapore have discovered that the mRNA COVID-19 vaccine may boost the immunity of survivors of the original SARS virus. This can be the key to creating a vaccine that works against all similar viruses.

The research team announced their findings from their small study on Wednesday New England Journal of Medicine.. They collected antibody samples from 8 SARS survivors before and after vaccination and had 10 vaccinated COVID-19 survivors, 10 unvaccinated COVID-19 survivors, and both viruses. Compared with antibody samples from 10 vaccinated individuals who did not.

Researchers have identified the SARS virus, four variants of SARS-CoV-2 (the virus that causes COVID-19), bats and pangolin, but have not yet caused the outbreak of the disease in humans.

Studies have shown that antibodies from vaccinated SARS survivors are the only ones that have effectively neutralized all 10 viruses.

Antibodies from vaccinated people who did not have the SARS virus also worked well against most viruses, but struggled against the three pre-emergent viruses.

SARS, or Severe Acute Respiratory Syndrome, is a disease caused by the SARS-CoV-1 virus. Between 2002 and 2004, SARS outbreaks reported more than 8,000 cases and nearly 800 deaths worldwide, including 251 cases and 44 deaths in Canada.

SARS-CoV-1 and SARS-CoV-2 viruses share 80% of their DNA. These viruses, and the other viruses investigated in this study, belong to the same subgroup of coronaviruses known as salvecoviruses.

Such vaccines not only provide immunity to future COVID-19 mutants, but also prevent new coronaviruses from jumping over species and causing another pandemic.

“‘Dream’ vaccines include SARS-CoV-2 and its known mutants of concern, as well as mutants of future concern and other coronaviruses that may cause serious human illness in the future. It will cover, “the authors write.

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Sources

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2/ https://www.ctvnews.ca/health/coronavirus/covid-19-vaccines-can-unlock-enhanced-immunity-in-former-sars-patients-study-1.5557002

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