Some COVID-19 antibodies attack the body, not the virus: research

COVID-19 antibodies in some recovered patients ignore the virus and attack the body instead — new studies suggest, as with autoimmune diseases.

Researcher at Emory University in Atlanta We examined 52 patients who had severe or severe attacks of the coronavirus and found that the immune system’s response to bugs reflected debilitating, lifelong illnesses such as lupus and rheumatoid arthritis. New York Times reported..

Of the 52 patients, who had no history of autoimmune disease, they produce molecules called “autoantibodies” that attack genetic material from cells rather than viruses.

Effects were recorded in nearly half of the patients studied, Outlet said. Research upload Preprint server MedRxiv Friday, still waiting for peer review.

Findings have scientists concerned that a false immune response can exacerbate the symptoms of COVID-19 — and the mysterious “long haulCase Consistent harvest In the world.

However, this study also provides important clues regarding treatment. Patients who produce autoantibodies, such as those that occur in lupus and RA, may respond better to drugs that treat these disorders, The Times reported.

“Some of these more aggressive drugs may attack the right patients more strongly and expect better results,” said Matthew Woodruff, the lead author of the paper and an immunologist at Emory University. I told the publication.

There is no cure for lupus or rheumatoid arthritis, but there are treatments that “reduce the frequency and severity of relapses.”

Other scientists who weren’t involved in the study said they weren’t surprised by the findings because the virus tends to produce autoantibodies.

“I’m not surprised, but it’s interesting to see it happen,” Akiko Iwasaki, an immunologist at Yale University, told The Times.

“Even moderate to mild illnesses can elicit this type of antibody response.”

Ann Marshak Rothstein, a lupus expert and immunologist at the University of Massachusetts Worcester who was not involved in the study, reiterated his comments to doctors in New York. Made in the post Previously, it was about the long-term effects of COVID-19 infection.

If the coronavirus autoantibodies are found to last as long as any other autoimmune disease, health problems can last a lifetime, doctors said.

“It never really cures lupus. There is flare, it gets better, there is flare again,” she said.

“And it may have something to do with autoantibody memory.”

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