Health
COVID-19ICU patients at risk of acute brain dysfunction, according to research
In this study, published in The Lancet Respiratory Medicine Journal, more than 2,000 COVID-19 patients admitted before April 28, 2020, had delirium and coma in 69 adult intensive care units in 14 countries. We tracked the incidence.
Sedative selection and suppression of family visits have played a role in increasing acute brain dysfunction in these patients, according to scientists led by scientists at Vanderbilt University Medical Center in the United States.
They said ICU delirium was associated with higher medical costs and a greater risk of death and long-term ICU-related dementia.
Nearly 82% of patients in this study were in a median 10-day coma and 55% were in a median 3-day coma.
Scientists said acute brain dysfunction lasted an average of 12 days.
“This is twice as much as it is in ICU patients other than COVID,” said study co-author Brenda Pun of VUMC.
Scientists believe that COVID-19 may make patients more susceptible to acute brain dysfunction.
However, they also pointed out that patient care factors, some of which are related to the pressure exerted on health care by the pandemic, also appear to play an important role.
With respect to COVID-19, scientists believe that new clinical protocols that have proven to help prevent acute brain dysfunction, which usually affects many critically ill patients, have been widely abandoned.
“Our findings clearly show that many ICUs have returned to sedation that does not follow best practice guidelines, and we need to speculate on the cause,” said Pun.
“Early reports of COVID-19 suggested that the lung dysfunction seen required unique management techniques, including deep sedation. In the process, important precautions against acute brain dysfunction were Some was done by the board, “she added.
Scientists analyzed patient characteristics from electronic medical records, as well as care practices and findings from clinical assessments, and approximately 90% of patients tracked in the study were invasively mechanically ventilated at some point during hospitalization. And found that 67% were ventilated on ICU day admission.
Patients who received benzodiazepine sedative infusions had a 59% increased risk of developing delirium, they added.
By comparison, the study found that patients who had family visits had a 30% lower risk of delirium.
“There is no reason to believe that the situation in these patients has changed since the end of our study,” said Platic Pandalipande, lead author of the study.
“These long-term acute brain dysfunctions can be largely avoided. The ICU team, among other things, needs to reduce sedation levels in these patients and return to frequent arousal and breathing tests, mobilization, safe face-to-face or virtual visits. There is, “added Panda Haripande. PTI VIS VIS
Disclaimer:- This story has not been edited by Outlook staff and is automatically generated from the news agency feed. Source: PTI
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