Health
“Killer” sperm try to poison rivals in a life-and-death race to reach the egg
mouse Sperm were caught trying to poison a competitor to first reach the egg.
the scientist Researchers at the Max-Planck Institute for Molecular Genetics in Berlin, the capital of Germany, analyzed rodent samples.
They found that some had a genetic mutation called a haplotype, which allowed them to move faster and more linearly. This variant-free sperm from the same mouse tended to be less productive and often slowly moved around in a circle.
Mutants are considered to be “selfish” genetic elements, and researchers Bernard Herrmann and his team have discovered how these sperms can benefit.
Sperm cells that carry haplotype mutants produce molecules that can interfere with other sperm cells.
Experts hope that this study will enable the development of treatments for male infertility.
The team also found a link between sperm success and a key protein in the body called RAC1, which plays a role in general cell movement and directs sperm cells to the egg.
Intracellular RAC1 levels need to be appropriate – if they are too high or too low, sperm cells will not move straight.
If the level of RAC1 is disturbed, their internal guidance system will fail, as will their desire to reach the egg.
It turns into a literal life-and-death competition.
Dr. Hermann said: “Sperm infertility is a major problem for male infertility. Investigating the level of this protein in human samples may help develop treatments for male infertility.”
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