Some blood pressure tablets can delay memory loss for up to 3 years

Elderly people taking certain types of hypotensive drugs have a high memory recall rate, suggesting that they can be used to slow down memory loss.

Researchers have found that treatment of people over the age of 50 with angiotensin II receptor blockers such as candesartan and irbesartan and ACE inhibitors such as ramipril and lisinopril reduces cognitive impairment by 19%.

According to the university, high blood pressure, also known as high blood pressure, is a risk factor for memory loss and dementia in the elderly. California, Irvine expert.

It is estimated that about one in three adults in the United Kingdom has high blood pressure, and studies have shown that treatment with certain medications can also improve memory.

Different types of drugs work differently to lower blood pressure, and some cross the blood-brain barrier and affect cognitive function.

Volunteers in this study of 12,500 adults over the age of 50 taking drugs that cross the blood-brain barrier improved their attention level after three years.

Researchers found that treating people over the age of 50 with angiotensin II receptor blockers such as candesartan and irbesartan, and ACE inhibitors such as ramipril (pictured) and lisinopril reduced cognitive impairment by 19%.

Elderly people taking certain types of hypotensive drugs have a high memory recall rate, suggesting that they can be used to slow down memory loss.Stock image

Main survey results

• Elderly people taking antihypertensive drugs that cross the blood-brain barrier showed better memory recall with up to 3 years of follow-up
• This is compared to people taking drugs that do not cross the blood-brain barrier, despite their high vascular risk.
• Adults taking antihypertensive drugs that did not cross the blood-brain barrier were able to pay more attention with up to 3 years of follow-up.

Angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), calcium channel blockers, and diuretics are different classes of blood pressure lowering drugs commonly used by patients.

Research author Dr. Daniel Nation, an associate professor at the University of California, Irvine Institute for Memory and Neurological Disorders, said:

“Studies of angiotensin II receptor blockers and ACE inhibitors suggest that these drugs may have the greatest benefit to long-term cognition.”

However, he added, “other studies have shown the benefits of calcium channel blockers and diuretics in reducing the risk of dementia.”

He said this was the first to compare the potential effects of antihypertensive drugs over time between drugs that cross the blood-brain barrier and those that do not.

The drug was evaluated for its effects on several factors, including attention, language, language memory, learning, and recall.

Dr. Nation said: ‘Hypertension occurs decades before the onset of dementia symptoms and affects blood flow to the brain as well as the body.

“Treatment of high blood pressure can later have long-term beneficial effects on brain health and cognitive function.”

The research team gathered information from 14 studies of more than 12,500 adults over the age of 50 in Ireland, the United States, Australia, Canada, Germany, and Japan.

They recall that older people taking blood-brain barrier-crossing blood pressure-lowering drugs have better memory recall with up to 3 years of follow-up compared to adults taking drugs that do not cross the blood-brain barrier. I found that it shows.

The study’s co-author, Dr. Jan Ho, said this is the strongest evidence to date linking ACE inhibitors and angiotensin-receptor blockers to better memory.

Researchers have found that people over the age of 50 taking angiotensin II receptor blockers and ACE inhibitors reduce cognitive impairment by 19%.Stock image

“People who are being treated for high blood pressure suggest that taking drugs that cross the blood-brain barrier may protect them from cognitive decline.”

The limitation of this analysis was that the author was unable to explain the racial / ethnic background differences based on the research available.

In addition, the proportion of men and women was high in the group that took drugs that crossed the blood-brain barrier.

This is important for future studies, as previous studies have shown that people of different racial / ethnic backgrounds can respond differently to different blood pressure medications. The area.

The survey results were published in the journal High blood pressure..

High blood pressure

High blood pressure, or high blood pressure, rarely presents with noticeable symptoms. However, without treatment, there is an increased risk of serious problems such as heart attack and stroke.

In the UK, more than one in four adults has high blood pressure, but many are unaware.

The only way to tell if your blood pressure is high is to check your blood pressure.

Blood pressure is recorded in two numbers. Systolic blood pressure (the higher the number) is the force by which the heart pumps blood around the body.

Diastolic blood pressure (low number) is the resistance to blood flow in the blood vessels. Both are measured in millimeters of mercury (mmHg).

As a general guide:

• Hypertension is thought to be over 140/90 mmHg
• The ideal blood pressure is believed to be between 90/60 mmHg and 120/80 mmHg
• Hypotension is considered below 90/60 mmHg
• Blood pressure measurements from 120/80 mmHg to 140/90 mmHg can mean that you are at risk of developing high blood pressure if you do not take steps to control your blood pressure.

If your blood pressure is too high, it puts extra strain on other organs such as blood vessels, heart, brain, kidneys, and eyes.

Persistent high blood pressure can increase the risk of many serious and potentially life-threatening conditions, including:

• Heart disease
• heart attack
• stroke
• heart failure
• Peripheral artery disease
• Aortic aneurysm
• Kidney disease
• Vascular dementia

Source: NHS

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