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Studies link Covid-19 mortality to lung viral load

Studies link Covid-19 mortality to lung viral load

 


Accumulation coronavirus In the lungs, a new study found that it was likely behind the sudden mortality rate seen in pandemics. This result contrasts with previous suspicions that co-infections, such as bacterial pneumonia and an overreaction of the body’s immune defense system, played a major role in increasing the risk of death. It was published in Nature Microbiology magazine.

The study is that dead people COVID-19 The lower respiratory tract had an average of 10 times the viral load of critically ill patients who survived the disease. Researchers, meanwhile, found no evidence to suggest that secondary bacterial infections were responsible for death, but warned that this could be due to frequent administration of antibiotics to critically ill patients. bottom.

“Our findings suggest that physical failure to cope with the large number of viruses that infect the lungs is a major cause of Covid-19’s death in a pandemic,” the release quoted. The lead author of the study, Imran Sulaiman, said.

This study was designed to clarify the role of secondary infections, viral load, and immune cell population in Covid-19 mortality. The release quoted Dr. Slyman as stating that the study provides the most detailed study of the lower respiratory tract environment in patients with coronavirus.

Researchers collected bacterial and fungal samples from the lungs of 589 men and women admitted to the NYU Langone facility. All necessary ventilation. This study analyzed the viral load of the lower respiratory tract in a subset of 142 people who also underwent bronchoscopy to clean the airways.

The study found that deceased patients produced an average of 50% less coronavirus-targeting immunochemicals than surviving patients.

Source: NYU Langone

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