Health
Extracts of the plant Corydalis yanhusuo may help fight opioid epidemics
As the opioid epidemic continues to die, researchers at the University of California, Irvine have identified plant extracts that may help fight opioid addiction.
The COVID-19 pandemic exacerbates the opioid crisis, with more people dying from overdose. Overdose of opioids has more than doubled the number of deaths in Orange County over the last decade.
According to the Orange County Healthcare Agency, 234 residents died from opioid overdose in 2011, compared to 499 in 2020. A major contributor to opioid deaths is the powerful synthetic drug fentanyl, which accounted for 381 of last year’s deaths. Orange County coroners did not test fentanyl or other synthetic opioid types in 2010, said Dr. Curtis Condon, research manager at the agency.
But YHS, plant extract CorydalisCan play a role in the fight against epidemics, allowing opioid addicts to potentially withdraw from drugs. According to the University of California, Irvine, YHS has been used as a painkiller in Chinese herbal medicine for centuries and can be purchased at specialty stores.
Olivier Siveli, a professor of pharmaceutical science at the University of California, Irvine and author of the YHS study, said the extract reduces pain and the development of opioid tolerance. Specifically, researchers have found that administration of morphine to YHS inhibits animal addiction, addiction, and tolerance.
“People take opioids, especially morphine, but when they take oxycodone and all other opioids on the market these days, people lose the effectiveness of opiates … they need to take more and more.” Said Civelli. “It’s dramatic because it makes people eat more and more and poses a risk of overdose.”
Civelli said researchers are now trying to determine how the extract blocks morphine resistance. He also hopes that further research will be done on how the drug works when ingested by humans.
“I hope people are interested in trying clinical trials,” says Civelli.
Over 93,000 people Death from drug overdose in the U.S. Almost 70,000 for opioids last year.Fentanyl, according to the California Department of Health Services Overdose accounts for more than one-third of deaths Between July 2019 and July 2020. Deaths from overdose have nearly quadrupled since 2018. In particular, officials pointed out that the homeless population was adversely affected by the rise in fentanyl.
More homeless People died in Orange County 2020 will be more than any other year. Opioids, especially fentanyl, were the cause of many overdose among homeless residents of Orange County. Of the 330 deaths, at least 90 were due to drug overdose, according to data from the coroner’s office.
Homeless people had few places to turn over last year and a half as a pandemic struck the county as shelters faced outbreaks and lacked resources.
“Many services and many resources we had before were completely wiped out with one hand by COVID,” said homeless advocate Tim Houchen. “We know that we have huge national problems with opioids, especially fentanyl, as well as homeless people, and I think many of these deaths are probably due to it. increase.”
Brazil writes in Times Community News.
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