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Studies find that older HPV vaccines reduce the incidence of cervical cancer by up to 87%

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The company logo of the pharmaceutical company GlaxoSmithKline will be seen at the Stevenage facility in the United Kingdom on October 26, 2020. REUTERS / Matthew Childs

November 3 (Reuters)-A young woman in her teens vaccinated against the human papillomavirus (HPV) at the old GlaxoSmithKline (GSK.L) A long-term study in the United Kingdom found that a product called Serverlix has an up to 87% lower risk of developing virus-related cervical cancer.

When vaccinated women are in their twenties, women who receive a series of injections between the ages of 12 and 13 have a higher incidence of cervical cancer than unvaccinated women who have been screened for malignancy. Was 87% lower.

Cancer rates were 62% lower when injected between the ages of 14 and 16 and 34% lower in women who were vaccinated between the ages of 16 and 18, researchers say. Reported to a medical journal.

When shots were given at ages 12 and 13, the rate of precancerous status was reduced by 97%, the study also found.

The findings “should greatly reassure those who are still hesitant about the benefits of HPV vaccination,” the researchers said.

The study, funded by Cancer Research UK, began in January 2006 on women screened for cervical cancer between the ages of 20 and 64, including women who received the Cervarix vaccine after it became available in 2008. I checked the registration data up to June 2019.

Data show that in almost 13 years, about 28,000 diagnoses of cervical cancer and 300,000 diagnoses of precancerous cervical intraepithelial neoplasia (CIN3) have been recorded in the United Kingdom.

Vaccinated young women had about 450 fewer cases of cervical cancer and 17,200 fewer cases of CIN3 than expected for unvaccinated women of the same age.

“We hope that these new results will drive the spread, as the success of the vaccination program depends not only on the effectiveness of the vaccine, but also on the proportion of the vaccinated population,” said the UK Health and Security Agency. Co-author Kate Soldan said.

Developed by GSK, Cervarix protects against two types of HPV that cause about 70% to 80% of all cervical cancers.

Since September 2012, Merck & Co’s (MRK.N) Gardasil, a 4-valent vaccine that protects against four types of HPV associated with cervical and head and neck cancer, is being used in the United Kingdom instead of Cervarix.

GSK also stopped selling Cervarix in the United States due to low demand as Gardasil dominates the world’s most profitable market.

Cervical cancer is rare in young women. A complete assessment of the effects of the vaccine requires follow-up as women grow older.

Report by Pushkala Aripaka in Bangalore.Edited by Nancy Rapid and Bill Berklot

Our criteria: Thomson Reuters trusts the principles.

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2/ https://www.reuters.com/business/healthcare-pharmaceuticals/older-hpv-vaccine-cuts-cervical-cancer-rate-up-87-study-finds-2021-11-03/

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