Health
Good news for heart failure patients taking COVID booster shots
According to a retrospective cohort study, vaccination against COVID-19 was associated with a significant reduction in severe outcomes in patients with heart failure (HF).
Completely vaccinated patients (HR 0.36, 95% CI 0.30-0.43) and fully vaccinated and boosted patients (HR 0.33, 95% CI) compared to unvaccinated HF patients. 0.23-0.48; PAnuradha Lala, MD and his colleagues at Mount Sinai School of Medicine in New York City both reported that <0.001) were unlikely to die of COVID.
In addition, vaccinated patients were less likely to be hospitalized (incidence ratio). [IRR] 0.68, 95% CI 0.65-0.71) and admitted to the ICU (IRR 0.63, 95% CI 0.58-0.68, PCompared to unvaccinated or partially vaccinated patients, the authors Journal of heart failure..
“The findings further emphasize that patients with heart failure need to take the vaccine seriously because infection with COVID-19 worsens the outcome, especially because previous studies have shown patients with heart, COVID. -19 Emphasizing the importance of receiving the full dose of the vaccine. Heart failure is 2.5 times more likely to die from the virus. “
She points out that she used these results to “educate reluctant patients” about the COVID vaccine, hoping that a heart disease specialist would do the same for the patient, and for the vaccine. He added that he had heard reports of heart failure patients who were afraid to be vaccinated. Related myocarditis.
“Until now, it has been difficult to explain to these patients that the cardiovascular benefits of vaccination far outweigh the risk of complications. Shows the substantial risk of not being vaccinated. There was no concrete evidence for this particular high-risk population and COVID-19 vaccination. “
In this study, Lala et al. Investigated data from patients with heart failure in a large medical system in New York City from January 1, 2021 to January 24, 2022. Patients were eligible if they had the ICD-10 code for heart failure. Diagnosis for the last two years. Vaccination status was determined “based on patient reports and vaccine card demonstrations”, either through electronic medical record entries or documents from clinicians or vaccination staff, they said.
Overall, 7,094 patients met the criteria: 45.1% were unvaccinated, 31% were vaccinated, 15% were vaccinated and boosted, and 9% were partially vaccinated. The average age was 73, 52% were male and 63% had Medicare insurance. Not surprisingly, 78% had “other cardiovascular disease,” 58% had hypertension, and 32% had type 2 diabetes.
Vaccinated and vaccinated / boosted cohorts are likely to be slightly older and whiter than unvaccinated and partially vaccinated cohorts, as well as other cardiovascular diseases, hypertension, lungs. The incidence of disease and diabetes was significantly higher.
During an average follow-up period of approximately 277 days, 904 patients died. Of these, 73% were unvaccinated or partially vaccinated.
The limits of the study included the fact that it was performed in one center and patients were not distinguished based on the type or stage of heart failure. In addition, potential unmeasured confounders may have influenced the results.
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Disclosure
Lala has disclosed support from Zoll. No other conflicts of interest have been reported.
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