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Monkeypox: A single dose of smallpox vaccine provides 78% protection, UKHSA reports

Monkeypox: A single dose of smallpox vaccine provides 78% protection, UKHSA reports

 


A single dose of MVA-BN (modified vaccinia Ankara-Bavarian Nordic) smallpox vaccine provides approximately 78% protection against monkeypox 14 days after vaccination, the United Kingdom Health Security Agency (UKHSA) said. I’m here.1

The agency’s analysis, published as a preprint, compares UK monkeypox cases and eligible gays, bisexuals, and men who have sex with men (GBMSM) from 4 July to 3 November 2022. ) examined vaccination uptake data in a cohort.

Of the 363 cases during this period, 8 had been vaccinated at least 14 days earlier and 32 had been vaccinated 0–13 days earlier. The remaining 323 were unvaccinated during this outbreak, giving him an estimated vaccine efficacy of 78%.

The agency said it was “the strongest UK evidence of vaccine efficacy to date” and is marketed as Imvanex in the UK and EU and Jynneos in the US. , provides one dose of the vaccine to healthcare workers caring for monkeypox patients and those who have been in close contact with monkeypox patients.2

Steve Russell, NHS National Director of Immunization and Screening, said: Although the risk of monkeypox remains low, we encourage anyone eligible to be vaccinated to come forward. ”

Since the outbreak began in May 2022, the UK has reported 3,720 monkeypox cases by 21 November.3 Vaccination coverage among eligible GBMSMs has increased steadily since July, reaching 47% by 9 October.

UKHSA consultant epidemiologist Jamie Lopez-Bernal said: A single dose of vaccine has been shown to provide strong protection against monkeypox. This shows how important vaccination is to protect yourself and others. ”

UKHSA says it will continue to investigate the duration of protection from one and two doses of the vaccine.

Sources

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2/ https://www.bmj.com/content/379/bmj.o2829

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