Health
VEXAS Syndrome | Geisinger
SEE syndrome, first explained In 2020, UBA1 It is genetic and can present with many inflammatory symptoms in adulthood, including skin rashes, joint swelling and pain, and inflammation of the lungs and blood vessels. Along with blood conditions such as anemia, blood clots, and low platelet count.
In the latest research, Journal of the American Medical Association (JAMA), Geisinger and a research team at the National Cancer Institute of the National Institutes of Health analyzed the genomic and electronic health record data of 163,096 participants enrolled in Geisinger’s. MyCode Community Health InitiativeOf this group, 1 in 13,591 UBA1 gene. All of these patients presented with anemia and other autoimmune, pulmonary, and cutaneous manifestations characteristic of VEXAS syndrome.
The study results show that VEXAS syndrome is more common in both men and women than originally thought, and the research team recommends more extensive testing. UBA1 A variant for people with non-specific inflammatory conditions and anemia.
“This study uses genetic and health data from patients who consented to participate in MyCode to answer important questions about the prevalence and health implications of recently reported but poorly understood diseases. It’s a great example of what you can answer,” said Carey, Ph.D., David J. Geisinger professor and principal investigator and lead author of the study.
Additional studies in diverse populations are needed to more precisely define the prevalence and characteristics of the disease, the team writes.
aMatch with Geisinger
Geisinger is committed to improving the health of the more than one million people it serves. Founded by Abigail Geisinger over 100 years ago, the system now includes 10 hospital campuses, health insurance with over 500,000 members, research institutes, and the Geisinger Commonwealth School of Medicine. With nearly 24,000 employees and more than 1,700 doctors, her Geisinger boosts the economy of her hometown of Pennsylvania by billions of dollars each year.Click here for details Facebook, Instagram, LinkedIn and twitter.
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