Sucralose is ‘genotoxic’ and linked to leaky gut: study

June 1, 2023 – A new study uncovers health concerns about the sugar substitute sucralose, with results so alarming that researchers have asked people to stop eating sucralose and He said the government should regulate more.

Sucralose is marketed under the brand name Splenda and is also used as an ingredient in packaged foods and beverages.

The results of the survey were released this week, Journal of Toxicology and Environmental Health, Part B. The researchers conducted a series of laboratory experiments exposing human blood cells and intestinal tissue to sucralose-6-acetate. This finding builds on previous research that has shown a link between sucralose and gut health issues.

Researchers have found that sucralose causes DNA breaks, putting people at risk for disease.They also have sucralose leaky gut syndrome, which means that the intestinal lining becomes worn and permeable. Symptoms include burning, indigestion, diarrhea, gas, and bloating.

If a substance damages DNA, it is called genotoxic. Researchers found that eating sucralose causes the body to produce a substance called sucralose-6-acetate, which the new study shows is genotoxic. The researchers also found trace levels of sucralose-6-acetate in ready-made products so high that they exceed the safe levels currently allowed in Europe.

“With increasing evidence that sucralose carries significant risks, it is time to revisit the safety and regulatory status of sucralose. At the very least, I encourage people to avoid products containing sucralose. ,” said researcher Susan Shiffman, Ph.D., adjunct professor of biomedical engineering at North Carolina State University. statement. “That’s something you shouldn’t eat.”

The FDA says sucralose is safe, explaining that it is 600 times sweeter than sugar and is used in “baked goods, beverages, chewing gum, gelatin and frozen dairy desserts.”

“To determine the safety of sucralose, FDA reviewed more than 110 studies designed to identify potential toxic effects, including studies on the reproductive and nervous system, carcinogenicity, and metabolism. It did,” the agency said. explained on that website. “FDA has also investigated human clinical trials to examine its metabolism and effects on people with diabetes.”

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