Health
Drugs Used to Treat Coronavirus in Cats May Be Effective in Humans: Study
Toronto-The drug used to treat a deadly disease caused by the coronavirus in cats may also be effective in treating humans diagnosed with COVID-19, According to new research..
Researchers at the University of Alberta described the drug as a protease inhibitor. Protease inhibitors work by blocking the ability of the virus to replicate and ending the infection.
“In order for the virus to replicate in the body, it needs to make a long protein, and because there are enzymes that cleave this protein, it blocks this protein from being cleaved, which causes the virus on Saturday on the CTV news channel, Joanne Lemu, professor of biochemistry at the University of Alberta and the lead author of the study, replicates in the body.”
Lemieux said the drug was first developed to prevent coronavirus infections in cats and can cause the viral disease feline infectious peritonitis (FTP). She said that during the 2003 outbreak of SARS, studies began on its potential use in humans.
“We decided to test this feline drug during the current SARS-CoV-2 outbreak to see if it works with the current virus in circulation,” Lemieux said. Says.
To do this, the research team synthesized compounds of the drug and tested them against SARS-CoV-2, a virus that causes COVID-19, in test tubes and human cell cultures.
“Certainly, the drug used in cats was effective in preventing viral replication in cells,” Lemieux said.
The drug has already been used to treat cats with coronaviruses, so research can bypass animal testing stages and move on to clinical trials of the drug, Remu said.
“We are in the process of obtaining approval from a clinical trial so that the drug can be used as an antiviral drug to treat patients with COVID-19,” she said.
Lemieux said he is convinced that the drug will be effective in treating humans with COVID-19 in the future. Meanwhile, she said she was studying different prescriptions for the drugs so that they would be more accessible.
“Currently, this requires injections,” she said. “If you want to deliver antivirals to the general public around the world, you probably need formulations that can be delivered orally or otherwise. Therefore, these are the types of drugs we are currently working on to make things a bit more manageable. That’s it.”
University of Alberta researchers Survey results have been released Thursday’s peer-reviewed journal, Nature Communications.
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