Asthma can be prevented by taking omega 3 fatty acids: Study

Researchers in a recent study found that eating more long-chain omega-3 fatty acids in the diet during childhood reduced the risk of developing subsequent asthma in children with common genetic mutations. Did.

The study, led by Queen Mary University of London, is being conducted in collaboration with the University of Bristol, the University of Southampton in the United Kingdom, and the Karolinska Institute in Sweden. In the UK, 1.1 million children (1 in 11) are currently being treated for asthma, and most adult asthma begins in childhood. The NHS spends about £ 1 billion annually on the treatment and care of asthma patients.

Professor Safeshaheen, senior author at Queen Mary University of London, said: “Asthma is the most common chronic disease in childhood and we currently don’t know how to prevent it. Inadequate diet can increase your risk of asthma. You have asthma. However, most studies so far have taken “snapshots” to measure diet and asthma in a short period of time. Instead, they measured their diet and tracked their children over the years to find out who developed asthma and who did not. ..

“Based on our findings, it’s not certain that eating more fish will prevent asthma in children, but nonetheless, few people are currently achieving recommended intakes, so the UK It is wise for children to eat more fish. “

Fish are of particular interest because they are a rich source of anti-inflammatory long-chain omega 3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

The study, published in the European Respiratory Journal, used data from the Children of the 90s, a large British birth cohort that recruited mothers who became pregnant in the early 1990s and have been tracking offspring since. They analyzed the association between EPA and DHA intake from 7-year-old fish (estimated by a food intake questionnaire) and the incidence of new cases of asthma diagnosed by doctors aged 11-14 years.

Long-chain omega 3 intake from fish was not associated with asthma in the entire cohort (4,543 people). However, the team investigated children with specific genetic makeup in more detail. More than half of children had common variants of the fatty acid desaturase (FADS) gene associated with low levels of long-chain omega-3 fatty acids in the blood. In these children, the higher their dietary intake of long-chain omega-3 fatty acids, the lower their risk of asthma. Comparing the upper and lower quartiles of long-chain omega 3 intake, the risk was 51% lower.

In addition, this finding was found in the Swedish Independent Birth Cohort Study (BAMSE).

Researchers warn that higher intakes of long-chain omega-3 fatty acids in childhood can prevent subsequent onset of asthma, as they only found an observational link. doing. The next step is to see if higher intakes reduce the risk of exacerbations in children who already have asthma.

This project was funded by Rosetrees Trust and The Bloom Foundation. The UK Medical Research Council, Welcome, and the University of Bristol provide core support for children in the 90s.

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