Health
Studies say overreactions in the immune system can cause “Covid Toes”
Immediately after the outbreak of the pandemic last year, doctors were puzzled by the proliferation of patients complaining of chilblains (lesions with painful toes and sometimes fingers), primarily teens and young adults.
The condition is now called the Covid toe. They were seen as yet another strange and obvious sign of illness, such as loss of smell and taste, even though most patients were tested negative for the coronavirus. Doctors had a hard time explaining the association.
Lesions are red or purple in Caucasians Often purplish Or the color people were brownish. They cause a painful burning sensation or itching, sometimes making it difficult for people to put on or walk.
Now a new study from France, Published in the British Journal of Dermatology, Covid sheds some light on the cause of the toes. Studies have shown that lesions can be a side effect of the immune system’s transition to overdrive in response to exposure to the virus, which can damage cells and tissues in the process.
French researchers analyzed blood samples and skin biopsies from 50 patients who first had chillbrain-like lesions in April 2020 and were referred to St. Louis Hospital in Paris. More than half of the patients showed other symptoms suggestive of Covid-19, such as coughing, shortness of breath, and loss of smell, but all patients were virus-negative on PCR.
The sample showed high levels of type 1 interferon. It’s a protein that activates the body’s immune system to fight viruses, but it can also cause damage. Researchers have also discovered high levels of antibodies that can inadvertently attack cells in the body itself.
Studies suggest that abnormal changes in the lining of blood vessels may also be involved in the lesion.
The relationship between coronavirus infection and chillbrain-like lesions is “still controversial,” the authors write. “The peak of chillbrain-like lesions with the peak of Covid-19 mortality in 2020 strongly suggests that this disorder is closely associated with SARS-CoV-2 infection.”
Covid’s toe description isn’t entirely surprising. One of the hallmarks of this disease is an overreaction of the immune system called a cytokine storm. This can ultimately cause more illness than the virus itself.
German scientists published a treatise last year stating that they found something powerful Localized interferon drive response Three young men who came with chilblains. The paper found that a man who tested negative for coronavirus may develop chillbrene weeks after the initial infection caused a mild or asymptomatic illness, and an immune response by interferon was early in the virus. A disease that has led to control and may have interfered with breathing.
According to dermatologists, people with Covid toes generally work well, are less likely to develop severe Covid, and the symptoms reflect a healthy immune response to the virus.
A new study suggests that treating Covid’s toes with topical or systemic anti-inflammatory agents may be effective.
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Sources 2/ https://www.nytimes.com/2021/10/06/health/covid-toes-cause.html The mention sources can contact us to remove/changing this article |
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