CDC Advisor Supports Moderna and J & J COVID Vaccine Booster: Shot

Healthcare workers will receive the Pfizer-BioNTech COVID-19 vaccine at the Life of Hope Center in New York City on Thursday.

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Michael M. Santiago / Getty Images

Healthcare workers will receive the Pfizer-BioNTech COVID-19 vaccine at the Life of Hope Center in New York City on Thursday.

Michael M. Santiago / Getty Images

A panel of experts advising the Centers for Disease Control and Prevention unanimously supported the deployment of Moderna and Johnson & Johnson COVID-19 vaccine boosters, in line with the Food and Drug Administration’s approval issued Wednesday. The Commission’s actions also support a mixed-and-match approach to booster vaccinations.

In the case of Moderna, the panel said boosters should be given to people under the same conditions as Pfizer-BioNTech boosters. It is intended for people over the age of 65, people in long-term care facilities over the age of 18, and people between the ages of 50 and 64 with related underlying illnesses. Boosters can be given to people aged 18-49 with certain medical conditions, and people aged 18-64 who are at work-related COVID-19 risk or who live in a particular facility.

For Johnson & Johnson, the panel advice was simpler. Boosters are recommended for people over the age of 18 at least 2 months after initial immunization.

The next step is for CDC Director Rochelle Walensky to issue a statement on the Commission’s recommendations and to take an official position from the public health agency. The director usually follows the recommendations of the CDC’s Immunization Implementation Advisory Board, but in rare cases she departs. Rejected aspects of the Commission’s decision For Pfizer boosters.

The CDC presentation and voting draft should use the same vaccine used for initial immunization as booster immunization, but if a primary vaccine is not available or a different vaccine is desired, the mixed-and-match approach is problematic. It states that it is not.

During the committee’s discussions, some members opposed this preference to boost with the same vaccine. They argued that a more tolerant approach to mix-and-match would facilitate the administration of additional immune doses.

After a short break later in the deliberations, CDC staff returned with a neutral, modified voting question as to which vaccine should be used as a booster for the J & J and Moderna vaccines. The revised question does not explicitly mention which vaccine should be used as a booster. This makes it clear how to mix and match boosters without any restrictions.

According to the CDC, more than 189 million people in the United States are fully vaccinated, accounting for about 57% of the population. According to CDC data, hospitalization rates are 9 to 15 times higher in unvaccinated adults than in vaccinated adults.

Still, there’s a reason to think that boosters can be useful for some groups of people.

Over time, Moderna’s effectiveness against coronavirus infection declined in the face of delta variants. Protection against hospitalization remains generally strong, but there is some reduction in older people.

For the J & J vaccine, the CDC pointed out that the defense against infection and hospitalization is fairly stable. However, this vaccine is generally less effective than the Moderna and Pfizer vaccines, allowing boosters to boost protection from the J & J vaccine to a higher level.

The Commission has addressed the risk-benefit trade-offs of some group boosters. People over the age of 65 get the most and have a relatively small increase in risk. With the modelna vaccine, protection remains fairly strong for young people, and the risk of heart inflammation is higher, especially in men.

Regarding the J & J vaccine, there was concern about rare blood clots after vaccination. This is a higher risk for young women. However, there are benefits to the booster as a whole, as it provides increased protection from the second dose.

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