Health
Shanghai Junshi Biosciences for Human Testing of Coronavirus Antibody Drugs
Beijing — Shanghai Junshi Biosciences has launched an early-stage study in China to test the possibility of antibody treatment against coronaviruses in uninfected people, the official newspaper Liberation Daily said in an online channel on Sunday. https://bit.ly/3eZhSWM
The investigational drug JS016 will begin human studies in the US in the second quarter of this year, in collaboration with Eli Lilly.
Junshi is one of the few biotechnology companies backed by global pharmaceutical giants working on antibody-based therapies to help people infected with the rapidly expanding new coronavirus, which kills nearly 400,000 people worldwide. It is one of companies and research institutes.
Junshi’s chief operating officer, Feng Hui, said the company’s antibodies were isolated from the blood of recovered patients and designed by researchers to ensure that healthy people at high risk of infection, such as health care workers and the elderly, are at high risk. He said he hopes to prevent people from getting the virus. ..
But because Fensi’s antibody drug is expected to contain larger amounts of expensive proteins in a single dose than vaccines, this product could be much more expensive than vaccines, and more commonly A prophylactic drug that is being tested for multiple candidates being used.
Fen said in an interview with Reuters before the announcement, “Vaccines and antibodies have their own consumers, and they can’t replace each other,” he said.
“While vaccines are cheap and suitable for national vaccination, older people with relatively weak immunity may not be as responsive to the vaccine as healthy adults and children,” Von said. “Antibodies can better protect those people from viruses.”
In order to manufacture the drug, Junshi fears that the outbreak of viruses may further disrupt logistics and supply chain bottlenecks, and instead of the usual 6 months, 12 months before delivery I ordered materials and items such as vials from an overseas supplier.
Fen needs further research to determine the amount of protein to use in a single dose, but Fun will be able to reach 100,000 by the end of the year “at all “We can make enough doses to handle it. One shot gives 1 gram of protein.
However, Feng warned that it was uncertain whether enough participants could be found to use this drug in a large human trial in late stages.
(Report by Roxanne Liu and Se Young Lee, edited by Gerry Doyle)
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