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WHO ceases weapons for hydroxychloroquine and lopinavir / ritonavir treatment for COVID-19

 


Who today accepted the recommendation of the International Committee of Solidarity Investigation to discontinue the hydroxychloroquinine trial and lopinavir / ritonavir. The theme of solidarity was established by the WHO to find an effective treatment for COVID-19 for hospitalized patients.

The International Steering Committee formulated a recommendation in the light of the evidence for hydroxychloroquine vs. standard care and for lopinavir / ritonavir over standard care from the provisional results of the solidarity trial, as well as to review the evidence from all trials presented at the WHO Summit. July on COVID-19 Research and Innovation.

These provisional study results indicate that hydroxychloroquine and lopinavir / ritonavir produce little or no reduction in the mortality of hospitalized patients with COVID-19 compared to the standard of care. Solidarity trial investigators will adjourn trials with immediate effect.

Provisional results for each of the drugs do not provide solid evidence of increased mortality. There were, however, some safety signals in the clinical laboratory findings of the additional study of the discovery, participants in the Solidarity trial. They will also apply in a peer-reviewed publication.

This decision applies only to the conduct of a solidarity study in hospitalized patients and does not affect a possible assessment in other hydroxychloroquine-lopinavir / ritonavir studies in non-hospitalized patients or as a pre-exposure or post-exposure to COVID-19 exposure. The provisional results of the solidarity are now ready for the review published in the review.

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