October 27, 2021
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Health
Somewhat common cognitive impairment after COVID-19 infection
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Disclosure: One research author reports that he receives personal fees from Atea Pharmaceuticals, Banook Group, and Sanofi, as well as grants from Arnold Consulting, Regeneron Pharmaceuticals, and Sanofi in addition to the submitted work. Other authors have not reported relevant financial disclosures.
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Cognitive impairment occurred relatively frequently within a few months of patients infected with COVID-19, according to the results of a cross-sectional study published in. JAMA network opened.
“We wanted to determine the prevalence of cognitive dysfunction in patients after COVID and whether cognitive dysfunction occurred throughout the spectrum of disease severity.” Dr. Jacqueline H. Becker, Clinical neuropsychologists and associate scientists in general internal medicine at Mount Sinai School of Medicine told Healio Neurology. “Most previous studies tended to focus only on inpatient COVID-19 patients when reporting on cognitive dysfunction, or using a very small number of patients. Mild, moderate. Or, I wanted to examine more samples of patients with severe COVID-19 to see if it was consistent with earlier reports. “
Becker et al. Data from 740 patients who survived COVID-19 and were treated in outpatient, ED, or inpatient hospitals (mean age 49 years, 63% female, mean time 7.6 months from COVID-19 diagnosis) I checked. Participants were 18 years of age or older, spoke English or Spanish, tested positive for SARS-CoV-2, were positive for serum antibodies, and had no history of dementia.Researcher evaluated Cognitive function Through well-validated neuropsychological measurements. They used logistic regression to examine the association between cognitive impairment and COVID-19 care sites, which adjusted for race and ethnicity, smoking, obesity index, comorbidities, and depression.
The results are processing speed (18%), executive function (16%), phoneme fluency (15%) and category fluency (20%), memory coding (24%), memory recall (23%). ) Indicates that the most serious defect has occurred. According to the adjusted analysis, inpatients were alert (OR = 2.8; 95% CI, 1.3-5.9), executive function (OR = 1.8; 95% CI, 1-3.4), and category fluency (OR = 3; 95). ) Has a high failure rate. % CI, 1.7-5.2), memory encoding (OR = 2.3; 95% CI, 1.3-4.1) and memory recall (OR = 2.2; 95% CI, 1.3-3.8) compared to outpatient groups. Those who have been treated with ED Outpatient setting.. Researchers reported that there was no significant difference in disability in other areas.
“Our findings suggest that a significant proportion of patients may experience cognitive impairment months after COVID-19, which may contribute to significant dysfunction. “We do,” Becker said. “There is concern that SARS-CoV-2 may increase the risk of neurodegenerative disease. There is still much to learn, but early identification of patients with cognitive impairment after COVID is cognitive. Due to the potential and potential opportunities for interventions such as rehabilitation, it is very important for management and proper resource allocation.
“For that, cognitive screening of patients after COVID-19 as standard treatment may be wise, regardless of age or severity of COVID-19,” Becker added.
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