Health
Probiotics for ear infections?Researchers show microbiota related to ear health
Growing studies suggest that there may be a link between probiotic bacteria and prevention of ear infections. The latest study to delve into this area was published in Microbiology Spectrum, which examined the nasal microflora associated with otitis media (otitis media) in Aboriginal children.
Background..
The authors pointed out that recurrent and chronic ear infections are disproportionately widespread in disadvantaged communities around the world, especially indigenous communities. In disadvantaged communities, this type of deafness is associated with adverse educational and social development, resulting in poor employment prospects and increased contact with the judicial system in adulthood. With all this in mind, researchers wanted a better understanding of the microbial ecology needed to identify new targets for treating and preventing ear infections.
Researchers at the University of Queensland previously used culture and species-specific quantifications to investigate nasal microflora in relation to ear health and otitis media (OM) in 103 Australian indigenous children. I was using it. They found that children with past or present OM / upper respiratory tract (URT) infections had a higher load of ear pathogens and a higher detection rate of rhinovirus.In contrast, Corynebacterium pseudodiphtheriticumand Doroci Granularum.. SlowIt was associated with upper respiratory tract and ear health. However, culture-based analysis may not be affected by microbial population structures or non-cultureable organisms. To address this limitation, researchers have used 16S rRNA NGS with existing culture data to address the broader bacterial microflora and its ear and nose health and illness in indigenous Australian children. I investigated how it relates.
the study
The study investigated the microbiota of 103 children aged 2 to 7 years from two communities in northern Queensland. Two children rejected the swabs, so 101 swabs were used for analysis.
Investigation result
Researchers have shown that the nasal microflora of Aboriginal children is associated with ear and nasal health.
“By focusing on the upper respiratory tract microflora of disease-resistant children, we were able to investigate the ecological network of bacterial interactions that appear to work together to protect against this condition. rice field.” The author, Dr. Seweryn Bialasiewicz, is a translation microbiologist and senior researcher at the Queensland Institute for Pediatric Infectious Diseases. “It was clear that these two groups of bacteria were not only present, but also needed to interact with each other to provide protection from middle ear infections.”..
Important point
- Healthy children without a history of OM Doroci Granularumand Corynebacterium Bacteria.
- Researcher detected OrnithobacteriumIn children with OM, it suggests a potential role as a novel ear pathogen in this population.
- In relation to OM status MoraxellaAlthough both groups had healthy ears at the time of wiping, they were relatively abundant in children with a history of OM compared to children without a history of OM.
- In a child with a healthy nose Moraxellaand Staphylococcus..
- There is a correlation between C. pseudodiphtheriticumAnd D. SlowA healthy child without rhinorrhea or past OM.
Bialasiewicz said he would like to use this information to find a protection mechanism and replicate it to support or prevent OM in children.
“Because it can take the form of molecules that can be used as therapeutic agents or as protective probiotics, these” good bacteria “are seeded in the nose to provide protection against incoming” bad bacteria. ” can.“Bialasiewicz explained.
sauce: Microbiology spectrum..
Flight. 9, no. 2 doi.org/10.1128/Spectrum.00367-21..
“Upper respiratory tract microbiome in ear and nose health and illness of Australian Aboriginal and Torres Strait Islanders”..
Author: A. Coleman et al.
..
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