Health
Infection with Covid-19 induces self-attacking antibodies that last up to 6 months after recovery.World news
As the world fights coronavirus disease (Covid-19) for two years, a new study in the United States shows that the infection induces self-attacking antibodies, whether mild or asymptomatic, for a long period of time. It became clear that it could last.
The study, published in the Journal of Translational Medicine, found that individuals previously infected with the Covid-19-causing virus (SARS-CoV-2) develop a wide variety of autoantibodies that attack individual organs and tissues. Was shown. Six months after full recovery.
In particular, the researchers in this study knew in advance that severe cases of Covid-19 could stress the immune system to the extent that self-attacking antibodies were produced.
Therefore, researchers argued that this latest study was the first to show that Covid-19 not only induces autoantibodies, but also persists.
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Justyna Fert-Bober, a research scientist in the Department of Cardiology at the Smit Heart Institute in the United States and co-author of the study, explains why the findings make Covid-19 a “particularly unique disease.” Said to shed more light on.
She further laid the foundation for various types of persistent Covid-19 symptoms in people whose patterns of “immune dysregulation” shown in the study results ultimately lead to a condition known as “Long Covid-19”. Said that it may provide.
As many as 177 people were hired for research by the team, with confirmed evidence of previous infection with SARS-CoV-2. Next, blood samples from these individuals were compared to blood samples from healthy people before the pandemic.
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The researchers found that all previously confirmed Covid-19 infections had elevated levels of autoantibodies (self-attacking antibodies). Some of these autoantibodies have been found in people with autoimmune diseases, a disease in which the immune system attacks its own healthy cells such as rheumatoid arthritis and lupus erythematosus.
Susan Chen, director of the Institute for Healthy Aging and co-lead author of the study at the Smit Heart Institute’s Department of Cardiology, said the team signaled autoantibody activity normally associated with chronic inflammation and injury. He said he found it. Certain organ systems and tissues, such as the skin, joints, and nervous system, are involved.
Following the findings, the research team is now ready to expand research to look for possible types of autoantibodies that are present in people with prolonged Covid-19 symptoms (or long Covid-19) and may persist. I have.
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In addition, because studies were conducted on people infected before the introduction of the Covid-19 vaccine, researchers asked whether autoantibodies would be produced in people with breakthrough infections (infected after vaccination) as well. To find out.
Chen has such a detailed understanding of autoantibody reactions and how “SARS-CoV-2 triggers and drives these variable reactions”, “these effects occur in people at risk”. He pointed out that it helps to find a way to “cure and even prevent”.
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