Health
Blood tests may detect Parkinson's disease before symptoms appear | Parkinson's disease
Researchers have developed a simple, “cost-effective” blood test that can detect Parkinson's disease long before symptoms begin to appear, according to the study.
Around 153,000 people live in Parkinson's disease in the UK, and the scientists who undertaken the study said the test could “revolutionize” the early diagnosis of Parkinson's disease, “paving the way for timely interventions and improved patient outcomes.”
Parkinson's disease is a progressive neurological condition in which neurons in the brain are lost over time. This leads to a decrease in chemical dopamine, which plays an important role in controlling exercise.
The new test, reported by the Times, costs £80, analyses small genetic material known as transfer RNA fragments (TRFs) in the blood, focusing on the repetitive RNA sequences that accumulate in Parkinson's disease patients.
We also see parallel reductions in mitochondrial RNA, which worsen as the disease progresses. Mitochondria are found in cells and produce energy.
By measuring the ratio between these biomarkers, the researchers said the tests “provide a highly accurate, invasive, rapid and affordable diagnostic tool, providing hope for early intervention and treatment that could change the course of the disease.”
On a scale where a score of 1 indicates a complete test and 0.5 indicates that the test is better than flipping the coin, the Times reported that the test is 0.86.
According to a study published in the journal, the best clinical test currently used in patients who are currently using early signs of the disease was 0.73. Natural aging.
This test uses the same PCR technology used during the pandemic to confirm covid cases. It works by amplifying the targeted genetic material. This allows detection.
“The findings represent a major advance in understanding Parkinson's disease, providing simple, minimally invasive blood tests as a tool for early diagnosis,” said Professor Hermona Solek of Hebrew University at the University of Jerusalem, who oversees the study. “By focusing on TRF, we have opened a new window to the changes in molecules that occur at the earliest stages of disease.”
Professor David Dexter, UK's research director for Parkinson's disease, said: “This study represents a new angle to explore to search for biological markers for Parkinson's disease, in which case the markers can be identified and measured in blood that is appealing to future patients-friendly diagnostic tests of Parkinson's disease.
“More work is needed to continue testing and verifying this possible test so that we can understand how we can distinguish between this possible test, particularly other conditions that have similar early signs to Parkinson's disease.”
The study was led by PhD Nimrod Mudler under the supervision of Edmond and Lily Safra Centre for Brain Science and Alexander Silverman Life Sciences at Hebrew University.
|
Sources 2/ https://www.theguardian.com/society/2025/apr/12/blood-test-could-detect-parkinsons-disease-before-symptoms-emerge The mention sources can contact us to remove/changing this article |
What Are The Main Benefits Of Comparing Car Insurance Quotes Online
LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos
 |
 |
 |