Health
Efficacy of Moderna Covid vaccine reduced to only 90% in US trials
Vials of the Moderna Covid-19 vaccine are being prepared at the Majesky Stadium in Reading, western London.
Moderna, a US biotechnology company, has announced that the COVID vaccine is 90% effective against all forms of illness and 95% effective against severe illness.
The new results come from an ongoing Phase 3 clinical trial involving more than 30,000 people across the United States, and the headline effectiveness figures are: New England Journal of Medicine During December.
The new number is based on 900 ruling COVID cases from the survey as of April 9, while the previous number was based on 185 cases.
The company’s press release did not show why it was less effective, but one reason could be the emergence of new concern mutants that are less susceptible to vaccine-induced antibodies. There is.
Moderna is working on two variant-specific boosters, and mouse studies have shown that they have induced an increased immune response. The results of these studies are posted online. Scientific treatise It is currently awaiting peer review.
“New preclinical data on mutant-specific vaccine candidates gives us confidence that we can actively work on new mutants,” said CEO Stephane Bancel.
According to the company, as of April 12, it has administered 132 million doses. vaccine Worldwide, including approximately 117 million doses to the United States.
Providing a second tranche of 100 million doses by the end of May, followed by another 100 million doses by the end of July, is on track.
The· the companyClinical trials in adolescents aged 12 to 17 years are now fully enrolled with 3,000 US participants, and pediatric trials in children aged 6 months to 11 years are from the United States. 6,750 participants continue to be registered in China.
© 2021 AFP
Quote: The efficacy of the model nacovid vaccine was obtained in a US study obtained on April 14, 2021 from https: //medicalxpress.com/news/2021-04-moderna-covid-vaccine-efficacy-falls.html ( 2021, April 14th) will drop to only 90%
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