Connect with us


Organ transplant recipients remain vulnerable to COVID-19 after the second dose of vaccine: study


Countries around the world are doing their best to increase population inoculation for COVID-19, with a particular focus on the high-risk sections. Almost all of these groups are believed to be well protected by the vaccine. Nonetheless, a new study states that organ transplant recipients at high risk due to immunodeficiency are vulnerable to SARS-CoV-2 even after receiving a second vaccination.

A follow-up to their previous work, according to a study by Johns Hopkins medical researchers, two doses of the COVID-19 vaccine provide some protection (54% overall) for patients with solid organ transplants. .. However, it is not enough to relax important safety measures such as physical distance and wearing a mask.

“Based on our findings, we recommend that transplant recipients and other immunocompromised patients continue to practice strict COVID-19 safety precautions after vaccination,” said the lead author of the study. Dr. Brian Boyarski emphasized in a statement.

Insufficient antibody levels


Lung (representative photo)Pinterest

When you receive a solid organ transplant, such as the kidneys, heart, or lungs, you are often prescribed medication to suppress your immune system. This is done so that their bodies do not reject the organs they receive. However, such treatments can affect the body’s ability of transplant recipients to make antibodies against foreign bodies. Unfortunately, it also contains defensive ones generated in response to the vaccine.

Before them Research Researchers, published in March 2021, evaluated the antibody-producing ability of participants who are organ transplant recipients. They received the first dose of one of the two mRNA vaccines, Moderna and Pfizer-BioNTech, for COVID-19. Unfortunately, only 17% of participants produced sufficient antibodies after a single double-dose course of the COVID-19 vaccine.

Evaluation of the effect of the second administration

In the current study, the authors investigated the immunogenic response in 658 transplant recipients after receiving a second dose of either vaccine. No participant was previously diagnosed with COVID-19 and completed a double-dose regimen between December 16, 2020 and March 13, 2021.

COVID vaccine

COVID-19 vaccine (representative photo)Pinterest

Scientists have learned that only 98 (15 percent) of the 658 participants have detectable antibodies 21 days after the first dose of the vaccine. These results were similar to those obtained in previous studies (17%).

Twenty-nine days after receiving the second dose, the number of participants with identifiable antibodies increased to 357 (54%) out of 658. After administration of both doses, 301 (46 percent) of the 658 participants had no detectable antibody. 259 participants produced antibodies only after receiving the second dose.

“After the second shot, the number of people with detectable antibodies increased, which was 54% overall, but in the second study, antibody levels reached levels sufficient to prevent SARS-CoV-2 infection. The number of transplant recipients was still good, lower than what is normally found in people with a healthy immune system, “Dr. Boyarski said.

Need for attention

New coronavirus

SARS-CoV-2 (representative photo)Pinterest

In addition, the team found that among the patients who participated, those who were younger, were not taking immunosuppressive drugs (including antimetabolites), and were receiving the Moderna vaccine. I also discovered that. These findings were similar to the associations witnessed in the single-dose study published in March.

“Given these observations, transplant recipients should not assume that two doses of vaccine guarantee more immunity to SARS-CoV-2 than after one dose.” Highlighting Dr. Dolly Segev, co-author Research..

Dr. Segev COVID-19 (New Coronavirus Infection) Vaccines in solid organ transplant recipients. He also concluded that adjustments to immunosuppressive therapy or more booster shots should be included to ensure that sufficient levels of antibody are produced in this population.


What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos

Pictures Credit


to request, modification Contact us at Here or [email protected]