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Studies show that new lambda variants may be vaccine resistant

Studies show that new lambda variants may be vaccine resistant

 


Lambda variantThe first confirmed COVID-19 mutation in Peru is rapidly emerging around the world and has been highlighted as a mutant of interest by government agencies such as the World Health Organization (WHO). However, new studies suggest that it may be resistant to some vaccines.

Pre-printed white paper We focused on mutations published in late July that distinguish the lambda mutants shown as C.37 in the S protein found in cellular receptor receptors.

Mutations in this location of the virus are associated with resistance to immunization efforts.

Using data from the Global Initiative for All Influenza Data Sharing, researchers have discovered three mutations within the lambda peplomer protein that may imply resistance to vaccine-induced antibodies in humans.

“Our results suggest that the RSYLTPGD246-253N mutation conferred resistance of the lambda variant to antiviral humoral immunity,” the report concludes.

The RSYLTPGD246-253N mutation specifically resists immunity from antibodies produced by the human body, along with two other mutations identified when synthesizing COVID-19 samples.

In particular, this study sampled genome sequences from South American countries such as Chile, Peru, and Argentina. Here, the lambda mutant is the predominant strain.

Chile’s primary vaccine Sinovac, Common Pfizer used in the United States-not BioNTech and Moderna shots

This study has not been peer reviewed.


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Sources

1/ https://Google.com/

2/ https://thehill.com/changing-america/well-being/medical-advances/567771-study-says-new-lambda-variant-could-be-vaccine

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