Health
Scientists destroying cancer with bacteria over 50 years ago
Cancer is the second leading cause of death in the world. Unfortunately, there is currently no real cure for it. Cancer is a group of numerous diseases characterized by the uncontrolled growth of abnormal cells. Scientists are trying to kill cancer cells using our body’s own immune system. This seems to be possible now.
Normally, our body’s immune system identifies and destroys foreign substances in our body. However, cancer cells have the ability to evade detection and form tumors. Fortunately, researchers at the University of Missouri have discovered new ways to help the body’s immune system overcome its deception and destroy cancer.
“Normal cells flag” do not eat “molecules recognized by immune cells, thereby preventing the destruction of normal tissue. However, some cancers also develop the ability to mimic normal cells and generate this “don’t eat me” signal. As a result, the immune system cannot recognize the cancer as defective tissue and leaves it alone, “explained Yves Chab, an assistant professor of bioscience at the University of Missouri.
Immunotherapeutic drugs essentially block the “don’t eat me” signal, allowing the immune system to kill cancer cells.
Fight Prostate Cancer Using Old Bacterial Strains
However, immunotherapy may not be effective against certain types of cancer, such as the prostate, which is highly immunosuppressive and can overwhelm the body’s immune system.
Chub seems to have unleashed a solution to this problem with the help of bacteria over 50 years ago.
According to Chub, the bacterium is genetically flexible and can be genetically modified to overcome patient-specific therapeutic limitations.
“I can imagine genetically modifying the bacterium so that it can specifically take advantage of the cancer’s unique vulnerabilities to unload treatments that kill it,” the researchers said. ..
In fact, scientists at the Cancer Research Center and the University of Missouri have already developed a genetically distinct, non-toxic Salmonella strain called CRC2631 to select and kill cancer cells. It is derived from a Salmonella strain that has been stored at room temperature for more than half a century.
Currently, Chub and other scientists are showing the potential use of CRC2631 to unleash the body’s immune system against prostate cancer.
Since CRC2631 preferentially colonizes tumor cells, the effect is primarily tumor-specific, Chub said, suggesting that it can be used to design and deliver patient-specific treatments.
Prostate Cancer: When Should I Talk to Your Doctor?
Prostate cancer is one of the most common types of cancer in men. It begins in the prostate, a small walnut-shaped gland in a man, producing semen that nourishes and transports sperm.
It mainly occurs in middle-aged and older men. It is estimated that about 60% of cases occur in men over the age of 65.
Like all cancers, the prostate has many risk factors, including family history, obesity, genetic changes, and exposure to certain chemicals. Common symptoms of prostate cancer include urinary problems, sexual problems, and pain in the pelvis, back, and chest. .. Therefore, feel free to consult your doctor if you have any of these symptoms.
Published: January 17, 2021 9:40 pm | Updated: January 17, 2021 9:41 pm
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