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A new analysis by a WHO expert group reaffirms that there is no link between vaccines and autism
A new analysis by the World Health Organization's Global Expert Committee on Vaccine Safety has found that, based on the available evidence, there is no causal link between vaccines and autism spectrum disorder (ASD). The conclusion reaffirms the WHO's position that childhood vaccines do not cause autism.
The Global Advisory Committee on Vaccine Safety (GACVS), established in 1999, brings together international experts to provide WHO with independent and authoritative scientific advice on global vaccine safety priorities.
The most recent analysis, discussed by the Committee on November 27, 2025, first focused on the relationship between thiomersal-containing vaccines and ASD and the association between vaccines in general and ASD. Evidence based on 31 primary research studies, published between January 2010 and August 2025, including data from multiple countries, strongly supports the positive safety profile of vaccines used in childhood and pregnancy and confirms the absence of a causal relationship with ASD.
The committee also assessed an overview of the potential health risks associated with aluminum-adjuvanted vaccines, drawing on studies conducted from 1999 to March 2023. In addition, it reviewed a recent large cohort study that analyzed data from a national registry of children born in Denmark between 1997 and 2018. In summary, the available high-quality evidence shows no association between the trace amounts of aluminum used in some vaccines and ASD, supporting continued use vaccines with aluminum adjuvants.
After review, GACVS reaffirms its previous conclusions from 2002, 2004 and 2012: vaccines, including those with thiomersal and/or aluminum, do not cause autism.
WHO advises all national authorities to rely on the latest scientific developments and ensure that vaccine policies are based on the strongest available evidence. Global efforts to immunize children represent one of the greatest achievements in improving lives, livelihoods and prosperity of societies. Over the past 50 years, childhood vaccinations have saved at least 154 million lives.
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