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COVID-19: CDC says “less than half” of positive coronavirus antibody tests are accurate

 


The US Centers for Disease Control and Prevention states that antibody tests used to assess whether people have been contaminated with COVID-19 can be inaccurate in up to half the time. New guidelines Post on their website.

Health Coronaville / USA

(Photo: Reuters / Brian Snyder)
Lawyer John Flow named him “Tennessee Red”, parked in a driveway in his home, and in a driveway in his home coronavirus disease (COVID-19) on May 26, 2020, in South Easton, Massachusetts, USA. Outbreak.

Antibody tests, also called serologic tests, seek evidence of an immune response to an infection. “Some people’s antibodies may be detected within a week of onset,” says CDC.

Also read: FDA approves two new coronavirus antibody tests: are these the answers?

they are Not accurate enough The CDC said it will be used to make important policy decisions.

“The serology results should not be used to make decisions about grouping people who live or reside in schools, dormitories, correctional facilities, etc.,” says the CDC.

The health agency has clarified that serology results should not be used to make decisions about returning to work.

Health authorities or health care professionals who use antibody tests use the tests they most trust The CDC said in a new guideline that it can find people and may need to test twice.

The health agency SARS-CoV-2 antibody Is expected to be relatively low, ranging from less than 5% to 25%, so tests at this point may have more false positive results and fewer false negative results.

Also read: [BREAKING] 18 New COVID-19 antibody discovered by the US Army. SARS antibody was also found

This is a frequent discussion by public health experts over the last few weeks, but the CDC points out the issue in its latest antibody testing advice.

false positive

False positives can make someone think they were contaminated when they were not. There is little evidence that an infection gives people immunity to a later infection. Still, doctors worry that if people get a positive test for antibodies, they may behave as if they were immune.

The new CDC guidelines are University of Minnesota And other organizations that warn against using antibody tests to make policy decisions.

The CDC explains why investigations can often be inaccurate. Much is involved in how the virus spreads in the population under study.

“For example, in a population with a prevalence of 5%, a test with 90% sensitivity and 95% specificity yields a 49% positive predictive value,” says CDC. Therefore, less than half of these positive tests will have antibodies.

On the other hand, the same test with a population with antibody prevalence greater than 52% will give a positive prediction greater than 95%. Therefore, less than 1 in 20 people who test positive will have a false-positive test result.

Therefore, as there are many cases in the population that doctors suspect, it is safer to use high-specificity tests that are less likely to cause many false positives, as the CDC states.

The Food and Drug Administration also effect Of antibody test.

Also read: COVID-19: False-negative coronavirus testing may be due to how the sample was collected, experts say

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