Health
Prostate cancer doctors call for changes in screening guidelines over concerns about undetected cases
Amid concerns that too many men are dying unnecessarily, there is an urgent need to rethink the way GPs screen for prostate cancer.
Key Point:
- Prostate is the most commonly diagnosed type of cancer in Australia
- Routine screening is not recommended for most men because of the risk of overdiagnosis.
- However, some doctors believe the guidelines are outdated and should be changed
Routine prostate cancer screening is not recommended for most men, but some experts are calling for changes in screening guidelines.
Dr. Peter Swindle, a urologist who specializes in prostate cancer, says, “There are patients who are angry, who are dying, who are underdiagnosed.
Prostate cancer has overtaken breast cancer as the most common cancer type in Australia, with an estimated 24,217 cases recorded this year alone, according to data from the Australian Institute of Health and Human Services (AIHW).
More than 3,500 men are expected to die from the disease this year, according to the AIHW, and in the six years to 2020, prostate cancer deaths increased 15.6%.
Some men told ABC they struggled to get regular medical screenings from their doctors.
One of them is Police Lieutenant Justin Falkiner, who lives in the rural town of Dubbo, New South Wales.
He has a family history of this disease. So did his father and his late grandfather.
So when he was 36, his doctor performed a blood test for prostate-specific antigen, known as PSA.
This test measures a patient’s PSA level. If the PSA level is too high for age, the patient will be tested further. A scan or biopsy is usually done to determine whether it is prostate cancer or a noncancerous condition such as infection or inflammation. prostate.
Falkiner’s test returned to the low range.
When he was in his early 40s, he asked his doctor for a re-examination, but was told that guidelines didn’t require him until he was 50.
“So stupidly, I didn’t ask for a second opinion.”
Prostate cancer can occur in families, and a genetic link has been suggested.
According to the American Cancer Society, a man’s risk of developing prostate cancer is more than doubled if his father or brother has it.
A ‘catastrophic’ diagnosis after a chance test
Mr. Falkiner returned two years later with another problem, and his PSA came back with a reading of 21 after his GP had a full bloodshot. PSA values above 3 should generally be retested within 3 months.
He was referred to a urologist, and a month later a repeat test showed his PSA had risen sharply to 27.
“At that point, my urologist hit the panic button,” he said.
He was diagnosed with stage 2 prostate cancer, which was considered an intermediate risk. During this stage, the cancer grows faster and can become mildly to moderately aggressive.
“Everyone has an opinion that ‘it’s not going to happen to me.’ I didn’t change,” he said.
“So… you may have been prepared for what you were going to say, but it was still shocking to hear those three words.”
Also weighing heavily on his heart was his family. His wife Christine and young children Joshua and Ava.
Given that Falkiner’s PSA level had risen rapidly, Falkiner’s urologist feared his cancer might have already spread to other parts of his body. Luckily it didn’t happen.
But his specialist was certain of one thing.
Why Prostate Screening Is Controversial
Screening for prostate cancer is a controversial area because of the risk of overdiagnosis and potentially ‘dangerous’ treatments, said Harman, professor of primary care cancer research at the University of Melbourne. John Emery says.
“Overdiagnosis actually means detecting prostate cancer that is relatively slow growing and would not have harmed a man if he hadn’t known about it.
“The transrectal biopsy that we have historically used can be harmful.
“So [there are] The harms of cancer treatment are also…especially erectile dysfunction and urinary incontinence. ”
That means doctors have to weigh the risks and benefits of treating cancer, which, if left untreated, could potentially have caused no problems.
But Dr. Swindle argues that modern technology will prevent many of these harms, and that MRI will reduce the number of unnecessary biopsies.
“In the past, 30 to 40 percent of men with insignificant cancers were receiving treatment. That’s now down to 6 percent in Australia,” he said.
But concerns about overdiagnosis of prostate cancer are impacting how GPs perform PSA testing, and Dr. Swindle is concerned that some are being diagnosed too late.
“I estimate that somewhere between 60 and 70 percent of my patients come to me with a late diagnosis that could have been discovered one to three years ago,” he said.
Conflicting Guidelines for Physicians
In Australia there are two main guidelines used by physicians. Developed by the Royal Association of General Practitioners of Australia (RACGP), Australia’s professional body for general practitioners, and by the National Health and Medical Research Council (NHMRC). A government-funded professional body that produces health advice.
RACGP is currently reviewing the guidelines, but an update is unlikely to be published until next year.
“Unfortunately, the GP bible, the RACGP Red Book, is in stark contrast to the NHMRC testing guidelines,” said Dr. Swindle.
“As a result, there is confusion within the GP community, where GPs are unable to determine whether men should be tested.”
RACGP guidelines (sauce) |
NHMRC guidelines (sauce) |
---|---|
Screening of asymptomatic (low-risk) men with a PSA test has not been clearly shown to outweigh the benefits and is not recommended. |
Men at average risk of prostate cancer should have a PSA test every two years from age 50 to 69. |
For men at average risk of prostate cancer: At screening request, inform patient of risks and benefits before proceeding. |
Men who have a father or brother diagnosed with prostate cancer should have a PSA test every two years between the ages of 45 and 69. |
For high-risk patients (one or more first-degree relatives diagnosed with prostate cancer or familial breast cancer younger than age 65 years): At screening request, assess patient risks and benefits before proceeding will let you know. |
Men with a father and two or more siblings diagnosed with prostate cancer should have a PSA test every two years from age 40 to 69. |
Dr. Swindle hopes the RACGP will provide better education to its members on how to use the PSA test to screen for prostate cancer and adhere to NHMRC guidelines.
He also wants pathology companies to follow these guidelines.
But RACGP president Karen Price doesn’t accept the criticism being made to the university.
“Urologists were already benefiting from triage done by general practitioners,” she said.
“We see a large proportion of asymptomatic men and have to have very difficult and rewarding conversations with them about what the risks and harms are.
Dr. Price said the changes to the guidelines to be published next year will be guided by the peer-reviewed evidence.
“We are trying to evaluate whether screening may be beneficial to more men than expected because the risk of diagnostic harm may be less.
“But it needs to be looked very closely … by a scientist who can really handle numbers and statistics and examine all the available evidence that comes out in the international literature.”
Recommendations may include enhanced surveillance for men with low-risk prostate cancer.
Prostate cancer group also calls for new guidelines
The Australian Prostate Cancer Foundation (PCFA) is also conducting an expert review of the NHMRC-approved clinical guidelines for PSA testing developed in 2016.
It is hoped that PSA testing will be expanded to men aged 70, stronger guidelines for those with a family history of the disease, and recommendations for annual testing.
The PCFA said, “The fact remains that if prostate cancer is accurately detected before it spreads, it can be effectively managed and treated, eliminating avoidable deaths. Update 2016 guidelines.” is critical to achieving this objective.”
The expert panel will also consider in detail changes to the age at which testing begins.
Sources 2/ https://www.abc.net.au/news/2022-09-23/prostate-cancer-routine-screens-for-men-needed-doctors-say/101453794 The mention sources can contact us to remove/changing this article |
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