Health
Pennsylvania State Medical College is working on a COVID-19 vaccine that can tolerate variants
The most troubling property of COVID-19 has turned out to be its ability to mutate to evade human defenses.
This makes it possible to vaccinate against COVID-19 or infect immune people who have never had it before.
But now, scientists at the Pennsylvania State University of Medicine say they are “one step closer” to developing a vaccine that could withstand future mutations, also known as mutations.
They focus on the COVID-19 spike protein, which allows the virus to enter human cells and cause disease.
Existing vaccines target part of the spike protein to induce antibodies that allow people to fight off the virus.
However, according to the researchers, “the mutation provides an escape route for the virus from neutralizing antibodies.”
Researchers believe they may have found a way to block the escape route.
“We identified regions of the spike protein that were least likely to mutate and used that information to design new proteins. It could be used to develop vaccines that provide broader protection against possible coronaviruses,” said one of the researchers, Nikolay Dokholyan, in a news release.
Researchers recently Their method and results were published in the scientific journal Advanced Functional Materials.
They said, “Further research will be done to optimize the design of the immunogen and the immune response. Once completed, it may one day be used as a vaccine candidate in clinical trials.”
Related:
COVID-19 Booster Mistake Leaves Central Pennsylvania Couple Feeling Unsafe and Unprotected
Court erred in asking UPMC Harrisburg to administer ivermectin to COVID-19 patients, ruling says
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