Health
Ozempic and Wegovy could be the latest breakthrough in Alzheimer's disease prevention
Semaglutide— diabetes and weight loss Drugs known by trade names such as Ozempic and Wegs— continues to show promise in treating a variety of other conditions.
Although recent research has revealed that these drugs may help stop symptoms, opioid addiction, smokingand even help people live longa new study published in the journal Alzheimer's Disease and Dementia: Journal of the Alzheimer's Association Semaglutide is now also associated with a lower risk of Alzheimer's disease.
For the study, researchers at Case Western Reserve School of Medicine analyzed three years' worth of electronic records of about 1 million Americans with type 2 diabetes. They compared patients prescribed semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonists – any of seven other antidiabetic drugs, including metformin, dipeptidyl peptidase-4 inhibitors (DPP-4i), and other GLP-1RAs (which mimic the effects of GLP-1) patients who are prescribed Patients prescribed semaglutide had a 40% to 70% reduced risk of being diagnosed with Alzheimer's disease for the first time compared to other antidiabetic drugs.
“The results are what we expected,” said Ron Shu, a professor of biomedical informatics at Case Western Reserve University and the study's principal investigator. luck.
Considering other studies showing that semaglutide helps; reduce inflammation in your body, Prevent neuron damagepromote weight losscontrol diabetesprevents cardiovascular disease— In addition to helping curb the urge to smoke and drink — Xu says the drug already lowers risk factors for Alzheimer's disease.
“If we can target these risk factors… semaglutide could be beneficial in preventing or delaying the symptoms and onset of Alzheimer's disease,” says Xu.
Dr. Xu clarified that the study was not aimed at determining whether semaglutide lowers the risk of Alzheimer's disease in people without diabetes.
“Diabetes itself is a risk factor.” [for Alzheimer’s]” she says. So Xu and her team wanted to see if semaglutide would lead to better outcomes than other diabetes drugs in people at high risk: people with diabetes.
The researchers cannot say that semaglutide reduces the risk of Alzheimer's disease, only that there is an association. Further research is needed.
But Xu is also optimistic about what these findings mean for people currently diagnosed with Alzheimer's disease. She says she wants to see if semaglutide can improve outcomes for people currently managing Alzheimer's disease symptoms, or if it has a therapeutic effect.
For more information about Alzheimer's disease, see below.
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Sources 2/ https://fortune.com/well/article/diabetes-weight-loss-drugs-ozempic-wegovy-lower-risk-alzheimers-disease/ The mention sources can contact us to remove/changing this article |
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