Is it a stomach insect disease? Modela is manufacturing norovirus vaccine -NATIONAL

As a terrible example Norovirus As the number of infected people in Canada and the United States is increasing rapidly, a light of hope is visible on the horizon. Researchers are moving forward to developing gastric virus vaccines.

The US pharmaceutical company modela has developed a MRNA-based norovirus vaccine candidate called MRNA-1403. The company stated in the announcement that this vaccine is designed to defend from multiple norovirus gene by instructing cells to generate virus particles that stimulate the immune reaction without causing infection. Ta. Media release in September 2024。

“Norovirus is an impact of millions of people around the world every year, causes serious symptoms, and in some cases, and may cause hospitalization,” he said. ) Stefan Bansel said in the release.

“By proceeding with our norovirus vaccine during our clinical trials, we provide new tools to prevent this high -infectious virus infection that gives a great burden on medical systems around the world. I'm approaching again.

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Norovirus, which is generally called stomach insects, seems to have given a greater blow to the Canadian people this year, and the number of infected people is higher than the past.

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last month, Spare data According to the Canadian Public Health Agency (PHAC), norovirus infections have been reported nationwide at a higher rate than the average of five years from 2019 to 2023.

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How to deal with the symptoms of norovirus with strong infectivity

And ontario's public health authorities Recently confirmed Norovirus has been detected by a group of 190 people who complained of gastroenteritis in the past week at the University of Guerph.

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Norovirus It is a very infectious virus that causes diarrhea and vomiting. Trends occur more frequently from autumn to winter, and usually causes vomiting, diarrhea, abdominal pain, body pain, headache, and fever. This symptom can cause dehydration, and may need to be hospitalized for those who have reduced immunity, the elderly, and children.

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Currently, there are no approved vaccines or antiviral drugs to fight norovirus.

However, modela wants to change this situation with vaccine.

The company's vaccines are now I have taken the third phase clinical trial, This test, known as the NOVA 301 Trial, is to evaluate the safety, effectiveness and immune reaction in adults.

The test will be registered for about 25,000 participants around the world, including individuals in the United States, Canada, Japan and the UK.

Modela, if a clinical trial proves that the vaccine is safe and effective, will submit a sales application to US health regulations in 2026, which could lead to the first vaccine approval for norovirus. Was stated.

Modela is not the only pharmaceutical company trying to fight abdominal insects.

VAXSTART is a biotechnology company that focuses on the development of oral vaccines. Norovirus vaccine is also under developmentThe candidate is currently under the early clinical trial.

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