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Total spending on statins and other LDL-C lowering therapies fell by 46% despite increased usage

 


A closer look at the data also noted that statin use increased by 23% from 2014 to 2018 and generic use increased by 35%. Meanwhile, the use of branded prescriptions fell by a whopping 92%. Overall spending on statins decreased 52% from 2014 to 2018.

“Despite these declines, Medicare spent $9.6 billion on the brand name statin during the study period, with an additional $2.1 billion ($1.4 billion in rebates) by switching to an equivalent generic option when possible. You could save money,” the authors write.

One clear example of the power of generics is what happened to Ezetimibe’s spending after the generic version hit the market in 2016. Brand ezetimibe prescriptions declined by 96%, he said. Overall, spending on Ezetimibe decreased 62% from 2014 to 2018.

On the other hand, total spend on PCSK9 inhibitors increased by 199% from 2014 to 2018.

“The pattern of uptake of PCSK9 inhibitors among Medicare beneficiaries is similar to that observed with other new cardiovascular therapies,” the authors write. “The increased use may be related to the expanded coverage of PCSK9 inhibitors and improved ease of prescribing from Medicare plans. However, the prices of PCSK9 inhibitors are still high and recent manufacturers Further investigation is needed to determine whether the proposed price reduction will accelerate its adoption.”

Complete analysis from JAMA Cardiology Is available here..

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