Health
Some food compounds may bind the Sars-Cov-2 enzyme
Chemicals in foods and beverages, such as green tea, chocolate, and mascadine grapes, have the ability to bind to certain enzymes and proteases in SARS and stop their function, according to a new study by a biologist at North Carolina State University. I know that. CoV-2 causing COVID-19 infection.
According to De-Yu Xie SurveyProteases, the corresponding authors of North Carolina State University and professors of plant and microbial biology, are essential for health and “cell and viral viability.”
Corresponding authors added that if the protease was withdrawn, the call would not be able to perform various important functions, such as replication.
Xie also seeks dietary supplements in foods or medicinal plants that constrain either the way the virus attaches to human cells or the growth of the virus in human cells, one of the focal points of their laboratory. I explained that.
(Photo: Robbie Bracco on AIX)
A new study by a biologist at North Carolina State University shows that compounds in foods such as muscadine grapes have the ability to bind and stop the function of certain enzymes or proteases in SARS-CoV-2. I will. COVID 19 infection.
Main “protease”
with this New researchScientists at North Carolina State University have performed both computer simulations and laboratory tests to show the so-called “main protease” or Mpro method. SARS-CoV-2 The virus reacted when faced with several different plant compounds whose antioxidant and anti-inflammatory effects had already been identified.
Mpro The above types of coronaviruses are required for the virus to replicate or replicate and assemble itself, Xie added, adding that the virus is destroyed and killed if it can “inhibit or deactivate” the proteases above. I added that it would be.
Computer simulations showed that the investigated compounds derived from green tea, two muscadine grape varieties, dark chocolate, and cocoa powder were able to find different parts of Mpro.
A research correspondent also explained that Mpro has parts that resemble “pockets” filled with the aforementioned compounds. When the pockets were full, proteases lost their essential role.
Compounds found in grapes, green tea, cocoa powder and dark chocolate
The same results were obtained in an in vitro laboratory experiment completed by Yue Zhu, a PhD student at North Carolina State University, in Xie’s lab.
In essence, the compounds found especially in muscadine grapes have been very successful in inhibiting the function of Mpro. On the other hand, those contained in dark chocolate and cocoa powder reduced the activity of Mpro by about 50%.
Meanwhile, the contained green tea gives a tested compound that binds to different parts of the Mpro’s pocket and overwhelms it importantly to suppress that task, Xie explained.
Specifically, muscadine grapes have these inhibitory chemicals in both seeds and skin. Plants use these compounds to protect themselves. So it’s not surprising, and plant skin has these beneficial compounds.
Plant flavonoids
Another important finding presented in this study was two plant flavonoids, including flavan-3-ols and flavan-3-ols. Proanthocyanidins or PA..
They are usually found in fruits, foods and beverage products such as grapes, strawberries, persimmons, cranberries, cocoa nuts, chocolate and green tea.
In essence, as studies have shown, common flavan-3-all aglycones in these plants are “epicatechin or EC, catechin or CA, epigallocatechin or ECG, galocatechin or GC, epigallocatechin or Includes EAF and afzelechin or AF.
Read again: Russian Institute announces 91.4% efficacy of Sputnik V vaccine
Check out more news and information about COVID-19 (new coronavirus infection) (# If there is no character limit, add parentheses when it first appears Science Times.
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