Health
Women are better than men who can fight Covid-19, thanks to hormones that boost immunity, chromosomes
Female COVID-19
Patients face less severe complications and are at lower risk of dying than male patients because of hormones and chromosomes that contribute to a stronger immune response, researchers say.
“The highlight of our study is how gender differences COVID-19 It’s linked to ACE2, “said Gavin Audit, senior author at the University of Alberta, Canada.
ACE2 is an enzyme that acts as a receptor that allows SARS-CoV-2 to enter the body, but it is also important in protecting against cardiovascular, lung, and kidney disease.
Read again: Women’s immune response may be better than men in combat COVID-19,Survey results
“Because of the chromosomes, women have two copies of the ACE2 gene, and men have only one copy,” Audit said.
This protects them from virus-related complications.
In this study, published in the American Journal of Physiology-Heart and Circulatory Physiology, the team explained that ACE2 is a gene linked to the X chromosome.
To avoid duplication, one X chromosome tends to be inactivated, but due to its location ACE2 escapes inactivation. That is, women have twice as many active genetic instructions to make ACE2.
Another gene that is twice as strong in women as this escape from X-chromosome inactivation is called the Toll-like receptor 7, an important part of the innate immune system.
“The strong presence of Toll-like receptors 7 in women explains why women’s immune system is stronger than men and can better tolerate viral infections, including the common cold,” said Audit. ..
“The phenomenon of human cold is true,” Audit added.
In the study, researchers report that men are facing more serious illnesses and worse consequences around the world.
They pointed out that women are more likely to face exposure to SARS-CoV-2 than men. For example, 70% of healthcare workers are women, which is not reflected in their results.
Read again: Women who are likely to follow COVID-19 Regulations such as wearing masks and washing hands more than men
“Women face more risks because of gender issues, so I’m relieved to know that women’s results aren’t bad. In fact, women are clearly better than men.” Oudit said.
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