Health
Diabetes drugs can help with weight management
About one-third of the participants lost 20% of their baseline weight, or about 46 pounds. This is similar to weight loss in patients undergoing obesity surgery, Kushner said.
“It’s the first time we have a drug that starts to approach even the weight loss we achieve with obesity surgery,” he said.
People who took the drug were more likely to experience nausea, diarrhea, vomiting, or constipation. About three-quarters of the study group had these side effects, compared to less than half of those who took placebo. After the study, participants reported better physical function, less pain, better blood pressure, and better glucose control.
Semaglutide is currently on the market for the control of diabetes and is approved for use at lower doses than used in this study. Pharmaceutical company, Novo Nordisk, Apply for FDA approval In December for a dose of 2.4 milligrams used for weight management. Based on the FDA’s standard timeline, the review can take up to six months, the company said.
According to, over 42% of Americans are obese To CDCThat means that your body mass index is 30 or higher. Obesity increases the risk of cancer, type 2 diabetes, heart disease, and stroke. However, there are few cures, and current medications require injections once, twice, or three times a day.
Julie Ingelfinger, MD, a nephrologist at Massachusetts General Hospital, and Clifford Rosen, MD, a researcher at Tufts University School of Medicine, write that semaglutide research is “another first step.” Accompanying commentary To The·New England Journal of Medicine..
However, they pointed out some limitations. For example, most of the participants were white, which does not reflect the population of the United States. In addition, the study has not investigated the long-term efficacy of sustained weight loss. Today’s drugs on the market often do not work well in the real world, and some are being pulled due to side effects.
“In short, there is still a long way to go to control the epidemic of obesity,” they write.
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