Vitamin B6, B12 deficiency in Parkinson’s disease patients linked to nerve damage

Neuropathy, or nerve damage, was associated with abnormally low levels of vitamins B6 and B12 in 3 people Parkinson’s disease, According to the case report.

“All patients were identified in one facility in a row within a year,” the researchers write. This suggests that the neuropathy associated with low levels of these vitamins “may be an unrecognized entity.” Therefore, the team emphasized the importance of measuring vitamin B6 and B12 levels when neuropathy is suspected.

“We should also consider monitoring B6 and B12 levels even in the absence of symptoms of neuropathy,” the researchers added. “Timely recognition and treatment of both vitamin deficiencies can lead to improved outcomes in these patients.”

Recommended reading

Report, “Neuropathy due to coexistence of vitamins B12 and B6 in patients with Parkinson’s disease: case series, ”Was published as a letter to the editor. Neuroscience journal..

Vitamin B6 and Vitamin B12 are essential nutrients for the body. Of particular note are that these vitamins are involved in some of the molecular processes used to make the signaling molecule dopamine.

Parkinson’s disease Caused Due to the death and dysfunction of dopamine-producing cells in the brain, and its standard process (((Levodopa And its derivatives) essentially involve giving the brain more raw material to make dopamine.

Researchers pointed out that high doses of levodopa or similar drugs may lead to an increased need for vitamins B6 and B12 to aid in the production of dopamine. This is because these molecules share several metabolic pathways that require a particular balance.

A team at the University of Rochester in New York described three Parkinson’s disease patients taking relatively high doses of levodopa (1 gram or more) with neuropathy: a 53-year-old man, a 75-year-old woman, 59 year old woman 1 year old woman.

After some levodopa treatment (between 3 and 10 years), all three patients developed symptoms of neuropathy such as numbness, tingling, and pain in the extremities.

In the first two, a supplement of this nutrient was given because the first test revealed low levels of vitamin B12. However, symptoms persisted in both patients, and further examination revealed abnormally low levels of B6.

Adding the B6 supplement along with the B12 supplement alleviated the symptoms of neuropathy.

According to researchers, these cases emphasize that “B12 supplementation may reveal B6 deficiency” in people with Parkinson’s disease because both vitamins are consumed in the process of making dopamine. ..

The third patient was found to have low B6 levels on the first test, and her symptoms were alleviated with B6 and B12 supplements.

“Current neuropathy work-up guidelines recommend folic acid screening. [folic acid, a type of vitamin B] And B12 deficiency, but not B6 deficiency, “the researchers write.

“Because coexisting defects can be more frequent in PD [Parkinson’s disease], If neuropathy is a concern, we suggest checking B6 levels in this population as well, “they conclude.

The team also emphasized the importance of measuring levels of B6, B12, and related molecules during and after treatment for all Parkinson’s disease patients.

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: [email protected]: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos