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DDW: Cholelithiasis may predict the incidence of pancreatic cancer-Consumer Health News

DDW: Cholelithiasis may predict the incidence of pancreatic cancer-Consumer Health News

 


Friday, May 13, 2022 (HealthDay News)-2022 According to a study published during Gastroenterology Week, in the year prior to the diagnosis of pancreatic ductal adenocarcinoma (PDAC), patients suffered from cholelithiasis six times more often than the general population. Presents. , Was held in San Diego from May 21st to 24th.

Marianna Papageorge, MD and her colleagues at the Boston Medical Center used surveillance, epidemiology, and end-results-Medicare (2008-2015) data to identify 18,700 patients with PDAC. We assessed the incidence of outpatients for cholecystectomy in the year prior to the diagnosis of cholelithiasis (cholelithiasis or cholecystitis) and cancer.

Researchers found that 4.7% of PDAC patients had cholelithiasis and 1.6% had a cholecystectomy the year before diagnosis. From a non-cancer cohort (99,287 per year), 0.8 percent suffered annual cholecystectomy and 0.3 percent underwent annual cholecystectomy. Compared to patients without cholelithiasis, PDAC patients with cholelithiasis were diagnosed at an earlier stage (stages I to II) (40.5 vs 47.9%) and underwent pancreaticoduodenectomy at a higher rate (40.5 vs. 47.9%). 12.9 vs. 17.6%).

“Improvement of differential diagnostic strategies may help combat the high mortality rate of PDAC by providing earlier stages of diagnosis and opportunities for earlier intervention and treatment of these patients,” the authors said. Is writing.

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