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Concept of breathalyzer for early detection of lung cancer

Concept of breathalyzer for early detection of lung cancer

 


Early detection is everything when it comes to lung cancer.

Emma Morris, a PhD candidate in Cancer Detection and Treatment at HMRI and Newcastle University, said many lung cancer patients are diagnosed when they are already at stage four.

“If we catch it while it's treatable, the success rate of treatment is about 70 percent,” she says.

Dr Lenny Goreham, who has been working on the project since teaching in Wellington, New Zealand, is collaborating with master's students Garima Dobhar, Dr Zarina Amin and now Emma to develop the lung cancer breathalyzer. I've been working on it.

Dr Goreham said: 'Until the 80s extracellular vesicles (EVs) were considered garbage, but we now know that almost all living cells release extracellular vesicles. can even communicate with cells and stimulate the site of cancer infection.”

Emma is currently working on studying breath samples from healthy patients to characterize EVs in healthy breath.

In the next step, the researchers will collaborate with the Hunter Cancer Biobank to create a library of breath samples from lung cancer patients that will allow them to isolate EV biomarkers specific to lung cancer.

The breathalyzer then tests for these biomarkers.

“We want it to be a device that people can breathe into and get a reading right away,” Dr. Gorham says.

“Lung cancer is typically diagnosed by imaging or bronchoscopy and confirmed by tissue biopsy. Doctors still want to visualize the cancer, but they prefer a breathalyzer to get the first reading. is a much less invasive screening method,” says Dr. Gorham.

About lung cancer

  • Lung cancer ranks 5thth Australia has the highest number of cancer diagnoses, with 14,782 new cases of lung cancer diagnosed in 2023.
  • Lung cancer accounted for 17% of cancer deaths in Australia in 2023.
  • It is estimated that by 2023, one in 20 people will be diagnosed with lung cancer by the age of 85.
  • There are two main types of lung cancer: small cell cancer and non-small cell cancer. 85-90% of lung cancers are non-small cell cancers.
  • Lifestyle factors such as current or past smoking, environmental or occupational factors such as exposure to second-hand smoke, asbestos, diesel exhaust, silica, and air pollution, and personal factors such as increasing age or family history of smoking can all may cause. Increased risk of developing lung cancer.

Sources

1/ https://Google.com/

2/ https://hmri.org.au/breathalyser-concept-aims-to-catch-lung-cancer-early/

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