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Investigate the origin of COVID-19

Investigate the origin of COVID-19

 


On December 30, 2019, the Emerging Infectious Diseases Monitoring Program notified the world of unexplained pneumonia in Wuhan, China (1). Since then, scientists have made remarkable progress in understanding the causative agent, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), its infection, pathogenesis, and mitigation through vaccines, treatments, and non-pharmaceutical interventions. Has been achieved. Further investigation is needed to determine the cause of the pandemic. Theories of both accidental release from the laboratory and the spillover effect of zoonotic diseases remain viable. Knowing how COVID-19 emerged is important to inform global strategies to mitigate the risk of future outbreaks.

In May 2020, the World Health Assembly requested that the Director of the World Health Organization (WHO) work closely with partners to identify the origin of SARS-CoV-2 ().2). In November, the terms and conditions for joint research between China and WHO were announced (3). Information, data, and samples from the first phase of the study were collected and summarized by half of the Chinese on the team. Other members of the team built on this analysis. Although there were no clear evidence of natural spillover or laboratory accidents, the team rated the zoonotic spillover from intermediate hosts as “likely” and in the laboratory. We rated the accident as “very unlikely.” [(4), p. 9].. Moreover, the two theories were not given a balanced consideration. Only four of the report and its appendix, page 313, addressed the possibility of an accident in the laboratory (Four). In particular, WHO Executive Director Tedros Ghebreyesus commented that the report on evidence supporting the accident in the laboratory was inadequately reviewed and provided additional resources to fully assess the potential. Proposed (Five).

As scientists with relevant expertise, we agree with the WHO Secretary-General (Five), The United States and 13 other countries (6), And the European Union (7) It is necessary and achievable to clarify the cause of this pandemic. Hypotheses about both natural and laboratory spillovers must be taken seriously until sufficient data are available. Appropriate investigations need to be transparent, objective, data-driven, include extensive expertise, be subject to independent monitoring, and be managed responsibly to minimize the impact of conflicts of interest. there is. Public health agencies and laboratories should likewise make their records publicly available. Investigators need to document the authenticity and source of the data at which the analysis is performed and conclusions are drawn so that independent experts can reproduce the analysis.

Finally, at the beginning of the pandemic, at this time of unfortunate anti-Asian sentiment in some countries, it was Chinese doctors, scientists, journalists, and citizens who shared important information about the spread of the virus with the world. Please note that it was. Often it costs a lot of personal money (8, 9). We need to show the same determination to promote a cool, science-based discourse on this difficult but important issue.

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