March 2, 2022
Read for 2 minutes
March 2, 2022
Read for 2 minutes
Disclosure: The author and Lawrence have not reported disclosure of relevant financial information.
Certain types of oral microbiota were associated with the development of hypertension, the researchers said. journal American Heart Association..
Of the 245 bacterial species analyzed, 10 were positively associated with accidental hypertension and 5 were negatively associated, according to researchers.
Michael J. Lamonte
“Periodontal disease and hypertension are especially prevalent in the elderly, so if we can establish a relationship between oral bacteria and the risk of hypertension, we may be able to enhance hypertension prevention by enhancing targeted oral care. . ” Michael J. LaMonte, PhD, MPH, A professor of epidemiology at the University at Buffalo, New York, and a collaborator at the University’s Department of Epidemiology and Environmental Health’s Women’s Health Initiative Clinical Center, said in a press release.
The cohort has complete information on the oral subgingival plaque microflora at baseline, blood pressure and hypertension status were assessed at baseline, and accidental hypertension was followed annually from the Buffalo Osteoperio study. Included 1,215 postmenopausal women (average age at baseline, 63 years).
The baseline is defined as 429 women with normotensive blood pressure, blood pressure below 120/80 mm Hg, and no antihypertensive drugs. Blood pressure in 306 is elevated and is defined as a blood pressure of at least 120/80 mmHg without the use of antihypertensive drugs. 480 people were diagnosed with hypertension and were treated with medicines.
Of the 735 women who were not diagnosed with hypertension at baseline, accidental hypertension occurred on average 375 in 375 during a 4-year follow-up period, according to the researchers.
In a cross-sectional analysis, LaMonte and colleagues found 47 of the 245 bacterial species that vary with baseline BP status (P <.05 All).
In a prospective analysis, 15 bacterial species were associated with accidental hypertension (P <.05 All). Of these, 10 were positively associated with accidental hypertension (age-adjusted HR per standard deviation, 1.1-1.16) and 5 were negatively associated (age-adjusted HR per standard deviation, 0.82-0.91). The researchers wrote that there was.
Results did not change with age, smoking, BMI, or baseline blood pressure.
Willy Lawrence
“We have come to better understand that health is affected by more than traditional risk factors that we know are very important. This paper is influenced by our environment. It suggests the need to gain a better understanding of the additional health factors that may affect our biology at the endothelial level. ” Willy Lawrence, MD, At the Research Medical Center at HC Midwest Health in Kansas City, Missouri, the chairman of the AHA’s National Hypertension Control Initiative Oversight Committee and Head of Cardiology said in a presentation. “Comprehensive research on hypertension needs to remain a priority for better understanding and coping with the condition.”
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