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Daily naps for the elderly associated with a 40% increased risk of Alzheimer’s disease

Daily naps for the elderly associated with a 40% increased risk of Alzheimer’s disease

 


March 25, 2022

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Researchers report that older people who take a nap for more than an hour a day have a 40% higher risk of developing Alzheimer’s disease than adults who take a nap for less than an hour a day. .. Alzheimer’s disease and dementia.

In addition, those who took a nap at least once a day had a 40% increased risk of developing AD compared to those who did not take a nap once a day. Yue Leng, PhDReported by an assistant professor of psychiatry at the Weil Neuroscience Institute, University of California, San Francisco (UCSF), and a colleague.They evaluated the longitudinal relationship between them Nap and cognitive aging..


Source: Adobe Stock.
Source: Adobe Stock.

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“We found that the association between excessive daytime naps and dementia remained after adjusting for the quantity and quality of sleep at night,” said Len, co-lead author of the study. It is stated in the UCSF press release. “This suggests that the role of the nap itself is important and has nothing to do with sleep at night.”

Leng et al. Evaluated 1,401 participants with a median age of 81 through a rush memory and aging project at the Rush Alzheimer’s Disease Center in Chicago. The center has monitored participants for up to 14 years.

Participants wore watch-like devices to track mobility and underwent a series of annual neuropsychological tests to assess cognition for up to 14 days each year. At baseline, 75.7% of participants had no cognitive impairment, 19.5% had mild cognitive impairment, and 4.1% had AD.

Studies show that for participants who did not develop cognitive impairment, daily naps increased by an average of 11 minutes per year. After the diagnosis of mild cognitive impairment, naps increased on average 24 minutes, which continued to increase up to 68 minutes after the diagnosis of AD.

When assessing participants who had normal cognition at baseline but developed AD 6 years later, and who had stable cognition throughout the study, Leng et al. We observed an increased risk of developing Alzheimer’s disease (HR = 1.2; 95% CI, 1.06-1.35). In addition, the more often you take a nap, the higher your risk of Alzheimer’s disease (HR = 1.23; 95% CI, 1.08-1.39).

“I don’t think there is enough evidence to draw conclusions about causality. It is the nap itself that caused cognitive aging, but excessive daytime naps are a sign of accelerated aging or the cognitive aging process. There may be, “says Leng. “It will be very interesting for future studies to investigate whether nap interventions can help delay age-related cognitive decline.”

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