COVID-19 severity increases in mildly obese patients

Greater COVID-19 severity and risk of death are higher in those with a Body Mass Index (BMI), according to a study published European Journal of Endocrinology.. Results show that BMI above age 30 was associated with significantly higher risk of respiratory failure, intensive care unit admission, and death in COVID-19 patients, regardless of age, sex, or other related illness Was shown. The current guidelines for identifying high-risk people in the UK set a BMI of 40, but these data suggest that people with a BMI above 30 should also be classified as at risk. I am.

Obesity is a worldwide pandemic associated with many diseases and an increased risk of death. Since the onset of the COVID-19 pandemic, several studies have linked obesity as a more severe effect of Sars-COV-2 infection and a risk factor for death. UK and US guidelines for identifying high-risk items have a BMI of over 40. However, these recommendations were necessarily based on small studies and limited data, given the novelty and rapid progression of the Sars-COV-2 pandemic.

Dr. Matteo Lottri and colleagues at Arma Martell Studio Lam University in Bologna, Italy, analyzed the outcomes of about 500 patients admitted at COVID-19. Again, they found that obesity was associated with a significantly higher risk of severity and mortality, but also found that more than 30 BMI were associated with these adverse consequences.

Dr. Lottoli comments. “Our study shows that all grades of obesity are associated with severe COVID-19 disease, suggesting that people with mild obesity should also be identified as at-risk populations. I am.”

A high BMI is associated with severe COVID-19 disease, but the cause has not been described. Impaired immunological reaction Virus infectionChanges in lung function and obesity-related chronic inflammatory conditions have all been suggested as links. The next step in this research is to understand these mechanisms.

“Our hypothesis is that the outcome of Sars-CoV-2 infection depends on the metabolic profile of the patient, obesity interlaces with diabetes, metabolic syndrome Is also involved,” says Dr. Rottoli.

“The BMI cutoff needs to be re-evaluated to identify everyone at high risk of serious infection and not to underestimate the potential population impact of SARS-CoV-2,” Rottoli said. infection, Especially in western countries where the obesity rate is high. “

Dr Rottoli recommends that people and healthcare professionals need to be aware of the increased risk of COVID-19 disease of any grade. obesity..

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Global COVID-19 Registry finds more severe COVID-19-related stroke and higher mortality

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Provided by the European Endocrine Society

Quote: COVID-19 severity is based on https://medicalxpress.com/news/2020-07-covid-severity-patients-mild-obesity.html on mildly obese patients (July 16, 2020) July 16, 2020)

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