Health
British boy receives world's first intracranial epilepsy treatment device
A British schoolboy with severe epilepsy has made medical history by becoming the first patient in the world to try out a new device implanted inside his skull to control seizures.
Neurostimulators send electrical signals deep into the brain. Oran Noorson's Daytime Seizures 80% increase.
Oran has Lennox-Gastaut syndrome, a form of treatment-resistant epilepsy that developed when he was three years old and has suffered dozens, or even hundreds, of seizures every day since.
His mother Justine said Oran had suffered a variety of seizures, including falling to the ground, shaking violently and losing consciousness – and at times stopping breathing and needing emergency medication to revive him.
The operation, which lasted approximately eight hours, took place in October 2023. It was part of a trial conducted at Great Ormond Street Hospital in collaboration with University College London, King's College Hospital and the University of Oxford.
Oran, now 13, was 12 at the time of the surgery.
Epileptic seizures are caused by abnormal electrical activity in the brain, and the device, which emits constant pulses of electrical current, aims to block or disrupt these abnormal signals.
The rechargeable device is attached to the skull and connects to electrodes deep in the brain to reduce seizure activity, according to the University College London.
This is the first clinical trial in the UK to measure this type of treatment in children with epilepsy. The CADET pilot (Children's Adaptive Deep Brain Stimulation for Epilepsy Trial) will now recruit three additional patients with Lennox-Gastaut syndrome. The trial is funded by the British Academy of Engineering, with 22 patients then taking part in the full trial, which will be funded by the GOSH charity and LifeArc.
Martin Tisdall, Honorary Associate Professor at University College London and Consultant Paediatric Neurosurgeon at GOSH, said: “For Oran and his family, epilepsy has completely changed his life, so to see him riding a horse and regaining his independence is truly amazing, and we couldn't be happier to be part of their journey.”
Deep brain stimulation (DBS) is a treatment that involves surgery to insert a small device that stimulates specific parts of the brain. DBS has been tried before to treat childhood epilepsy, but previously a neurostimulator was inserted in the chest and wires were threaded to the brain.
(With inputs from PTI)
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Sources 2/ https://www.indiatoday.in/health/story/uk-boy-receives-worlds-first-epilepsy-device-in-skull-2557816-2024-06-25 The mention sources can contact us to remove/changing this article |
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