Connect with us

Health

Genetic mutations linked to ADHD and Parkinson's disease, Queensland leads research into brain size

Genetic mutations linked to ADHD and Parkinson's disease, Queensland leads research into brain size

qq

 


An international DNA and brain structure study led by Queensland researchers has revealed the causes of attention-deficit hyperactivity disorder (ADHD) and Parkinson's disease.

Approximately 1 in 20 Australians have ADHD, while Parkinson's disease affects an estimated 10 million people worldwide, with approximately 38 Australians diagnosed with the severe, incurable, progressive movement disorder every day. has been done.

Both of these conditions are on the rise worldwide and have a deep and serious impact on those diagnosed.

The study, the largest of its kind, used genetic testing and saliva testing to determine how genetic mutations affect the structure of the brain.

Queensland Institute of Medical Research (QIMR) Berghofer Associate Professor Miguel Renteria and PhD candidate Luis Garcia-Marin led 189 international researchers to combine brain DNA data from 76,000 participants. MRI scans were analyzed.

The results of this study were published today in the journal Nature Genetics.

“This is the largest and most geographically diverse genetic study of human…brain volume,” García-Marín said.

“75,000 people from 19 countries underwent MRI scans and provided saliva samples for DNA genotyping, allowing us to identify genetic variations that determine the volume of specific brain structures.”

A man standing with his arms crossed.

Luis García-Marín from QIMR Berghofer says this is the largest study of its kind. (Supplied)

Analyzing the “deep brain”

Garciamarín said they analyzed key subcortical regions, also known as the “deep brain,” which are “crucial in our daily lives.”

These include memory formation, emotional regulation, motor control, and sensory processing.

Garciamarin said they observed more than 254 genetic mutations that affect important parts of the brain and can increase the risk of both Parkinson's disease and ADHD.

“Some of these genetic variants increase or decrease the risk of ADHD and Parkinson's disease,” Garcia Marín said.

“A large brain volume tends to increase the risk of Parkinson's disease later in life, and a small brain volume tends to increase the risk of ADHD.”

A man in a black T-shirt sitting at a desk.

Associate Professor Miguel Renteria says more research needs to be done to confirm the link. (Supplied)

Associate Professor Miguel Renteria said this provides important insight into how to intervene.

“There is strong evidence that ADHD and Parkinson's disease have a biological basis, and this study is a necessary step to understanding and ultimately treating these symptoms more effectively.” said.

“By understanding how genes determine brain structure, we will be able to better prevent, diagnose and treat these conditions in the future,” he said.

García-Marín said the discovery was important, but more research was needed to link genes to various diseases.

“Scientists around the world will be able to use what we have learned in this study to continue their research…particularly into the genetics of mental health disorders,” he said.

Sources

1/ https://Google.com/

2/ https://www.abc.net.au/news/2024-10-22/qld-adhd-parkinsons-qimr-berghofer-brain-size/104500768

The mention sources can contact us to remove/changing this article

What Are The Main Benefits Of Comparing Car Insurance Quotes Online

LOS ANGELES, CA / ACCESSWIRE / June 24, 2020, / Compare-autoinsurance.Org has launched a new blog post that presents the main benefits of comparing multiple car insurance quotes. For more info and free online quotes, please visit https://compare-autoinsurance.Org/the-advantages-of-comparing-prices-with-car-insurance-quotes-online/ The modern society has numerous technological advantages. One important advantage is the speed at which information is sent and received. With the help of the internet, the shopping habits of many persons have drastically changed. The car insurance industry hasn't remained untouched by these changes. On the internet, drivers can compare insurance prices and find out which sellers have the best offers. View photos The advantages of comparing online car insurance quotes are the following: Online quotes can be obtained from anywhere and at any time. Unlike physical insurance agencies, websites don't have a specific schedule and they are available at any time. Drivers that have busy working schedules, can compare quotes from anywhere and at any time, even at midnight. Multiple choices. Almost all insurance providers, no matter if they are well-known brands or just local insurers, have an online presence. Online quotes will allow policyholders the chance to discover multiple insurance companies and check their prices. Drivers are no longer required to get quotes from just a few known insurance companies. Also, local and regional insurers can provide lower insurance rates for the same services. Accurate insurance estimates. Online quotes can only be accurate if the customers provide accurate and real info about their car models and driving history. Lying about past driving incidents can make the price estimates to be lower, but when dealing with an insurance company lying to them is useless. Usually, insurance companies will do research about a potential customer before granting him coverage. Online quotes can be sorted easily. Although drivers are recommended to not choose a policy just based on its price, drivers can easily sort quotes by insurance price. Using brokerage websites will allow drivers to get quotes from multiple insurers, thus making the comparison faster and easier. For additional info, money-saving tips, and free car insurance quotes, visit https://compare-autoinsurance.Org/ Compare-autoinsurance.Org is an online provider of life, home, health, and auto insurance quotes. This website is unique because it does not simply stick to one kind of insurance provider, but brings the clients the best deals from many different online insurance carriers. In this way, clients have access to offers from multiple carriers all in one place: this website. On this site, customers have access to quotes for insurance plans from various agencies, such as local or nationwide agencies, brand names insurance companies, etc. "Online quotes can easily help drivers obtain better car insurance deals. All they have to do is to complete an online form with accurate and real info, then compare prices", said Russell Rabichev, Marketing Director of Internet Marketing Company. CONTACT: Company Name: Internet Marketing CompanyPerson for contact Name: Gurgu CPhone Number: (818) 359-3898Email: cgurgu@internetmarketingcompany.BizWebsite: https://compare-autoinsurance.Org/ SOURCE: Compare-autoinsurance.Org View source version on accesswire.Com:https://www.Accesswire.Com/595055/What-Are-The-Main-Benefits-Of-Comparing-Car-Insurance-Quotes-Online View photos

ExBUlletin

to request, modification Contact us at Here or collaboration@support.exbulletin.com